Q1R1N5
Gene name |
hldD |
Protein name |
ADP-L-glycero-D-manno-heptose-6-epimerase |
Names |
ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME |
Species |
Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) |
KEGG Pathway |
csa:Csal_0008 |
EC number |
5.1.3.20: Acting on carbohydrates and derivatives |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1R1N5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1R1N5-F1 | Predicted | AlphaFoldDB |
No variants for Q1R1N5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q1R1N5 | |||||
No associated diseases with Q1R1N5
1 regional properties for Q1R1N5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | NAD-dependent epimerase/dehydratase | 2 - 246 | IPR001509 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.1.3.20 | Acting on carbohydrates and derivatives |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP-glyceromanno-heptose 6-epimerase activity | Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose. |
| NADP binding | Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ADP-L-glycero-beta-D-manno-heptose biosynthetic process | The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate. |
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIVVTGGAGF | IGANLVKALN | ARGREDVLVV | DDLSDGTKFV | NLADCTLGDY | LDKDDFLARV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KAELRGEPSE | LPPIEAIFHE | GACSDTTEWD | GKFMLENNFE | YSKVLLHFCQ | YKRIPFLYAS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SAATYGGSEV | FVEAPEHEKP | LNVYGYSKLL | FDQYVRVHWE | SFDAQVVGFR | YFNVYGPREQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HKGKMASVAY | HHHSQVKRGE | NPKLFGAWDG | YEAGMQSRDF | VYVGDVVDVN | LWCLDHPEVS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GIFNLGTGRA | EPFKAIAETV | IDYYATGKID | YIDFPEELKG | RYQSYTRADI | SRLREAGYKA |
| 310 | |||||
| EFKTVREGVS | AYLDWLNG |