Q1QX69
Gene name |
msbA |
Protein name |
ATP-dependent lipid A-core flippase |
Names |
Lipid A export ATP-binding/permease protein MsbA |
Species |
Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) |
KEGG Pathway |
csa:Csal_1586 |
EC number |
7.5.2.6: Linked to the hydrolysis of a nucleoside triphosphate |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1QX69
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1QX69-F1 | Predicted | AlphaFoldDB |
No variants for Q1QX69
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q1QX69 | |||||
No associated diseases with Q1QX69
1 regional properties for Q1QX69
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Large-conductance mechanosensitive channel, conserved site | 11 - 24 | IPR019823 |
Functions
| Description | ||
|---|---|---|
| EC Number | 7.5.2.6 | Linked to the hydrolysis of a nucleoside triphosphate |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled lipid transmembrane transporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRNATSWSLY | RRLLSYVRPY | WKAFLAAVVG | YAIYAASSTA | LAEMMKRLID | GIQNPDAAFR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LMLPLFVIGM | FAARGVGTFL | GTYYMSDVAR | NVVHALRCEV | FNHMLRLPGR | FFDMHSSGHL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSRVTYHVEQ | VTGAATNAIT | IILREGLFVI | GLVSYLLWTN | WMLTLIFMAV | TPLIGLVVNY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSKRFRRLSR | RIQNSMGDVT | HVASEALSGY | RVVRTHGAEA | YEKARFAEAS | DYNREQSMKV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALTKAVSTPV | IQLLVALSLA | GLVWLAMSPA | LMASMTPGEF | VAFITAASLM | AKPVRQLTEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NSTIQKGLSA | SQELFGLLEQ | PPEVDEGSYV | PARIDGRVRF | EGVRFRYGED | QAEVLKGIDL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DVPQGEMIAI | VGRSGSGKST | LVSLMPRFYR | PTEGRVLLDD | VDIQEYALSP | LRQRIALVSQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QVTLFNTTIA | ANIAYGHPDA | DREAVESAAR | SAYAHEFIER | LPNGYDTVVG | DNGVMLSGGQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RQRLAIARAI | FKDAPLLVLD | EATSALDTES | ERYIQQALER | VCRGRTTFVI | AHRLSTIERA |
| 550 | 560 | 570 | |||
| DRILVMEQGE | IIESGTHGEL | LAQDGAYAAL | HQLQFQEAE |