Q1QA45

PR
Gene name
hemE
Protein name
Uroporphyrinogen decarboxylase
Names
UPD, URO-D
Species
Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)
KEGG Pathway
pcr:Pcryo_1681
EC number
4.1.1.37: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1QA45

Entry ID Method Resolution Chain Position Source
AF-Q1QA45-F1 Predicted AlphaFoldDB

No variants for Q1QA45

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1QA45

No associated diseases with Q1QA45

3 regional properties for Q1QA45

Type Name Position InterPro Accession
conserved_site Flavodoxin, conserved site 5 - 21 IPR001226
domain Flavodoxin/nitric oxide synthase 3 - 172 IPR008254
domain Flavodoxin domain 4 - 153 IPR026816

Functions

Description
EC Number 4.1.1.37 Carboxy-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
uroporphyrinogen decarboxylase activity Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.

1 GO annotations of biological process

Name Definition
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSASDNNNSL EQKFAPLKND RLLRALRFEP IDTTPVWMMR QAGRYLPEYK ATRAEAGDFM
70 80 90 100 110 120
SLCKDTARAT EVTLQPLRRY DLDAAILFSD ILTIPDAMGL GLYFEAGEGP KFKHPIRQQA
130 140 150 160 170 180
DLDRLPVLDV NDSLDYVMRA VTSIRTALNG QVPLFGFSGS PWTLATYMIE GGSSKDYRYT
190 200 210 220 230 240
KGFLYSNPDF LHQLLDKLAT SVIDYLDAQV VAGAQILQIF DSWGGALGHR QFIDFSHAYN
250 260 270 280 290 300
KRIVAELKVR HPEIPVVLFT KGGGLWLDIQ ADSEADALGL DWTMPIDRAR QVLTESQRQL
310 320 330 340 350 360
TKHHKKLQSS KAIQGNLDPA TLYGSPATIR AEVNAMLDSA YANGEKTGYV ANLGHGITQW
370
VNPDNAKVFI DAVHDYKI