Q1LWL8
Gene name |
mycl1b |
Protein name |
Protein L-Myc-1b |
Names |
|
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:567762 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1LWL8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1LWL8-F1 | Predicted | AlphaFoldDB |
No variants for Q1LWL8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q1LWL8 | |||||
No associated diseases with Q1LWL8
3 regional properties for Q1LWL8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Myc-type, basic helix-loop-helix (bHLH) domain | 321 - 379 | IPR011598 |
| domain | Transcription regulator Myc, N-terminal | 17 - 178 | IPR012682-1 |
| domain | Transcription regulator Myc, N-terminal | 175 - 267 | IPR012682-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| developmental process | A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P04198 | MYCN | N-myc proto-oncogene protein | Homo sapiens (Human) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPGISASASR | IKKWEMEEYD | QYQHYFYDDH | NLDEDFFKST | APSEDIWKKF | ELVPTPPMSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VRILEGSGPS | PGDRLEWVSQ | FLGQDDEQEG | LCKLNAEETL | ENLSSIIIQD | CMWSSFSASQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QLEKVVSERL | SCSAQSKLSG | KAQCVPADVP | ALNSLATDCV | DPAAVLTFPL | SSSCKKQVSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GSESRTDSSD | DEEIDVVTVE | HKQNKSRLVN | ARKPVTITVR | ADPHDPCMKR | FHISIHQQQH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NYAARSPDSY | PEEEPPRKKI | RQEIVQPRLA | STPQTPERKS | PLPSPSVPAQ | SPTVSASPTH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TSYHLKSQPS | SPQSSDCEDT | DKRKTHNFLE | RKRRNDLRSR | FLALRDEIPG | LVDCPKTPKV |
| 370 | 380 | 390 | 400 | ||
| VILTKATEYL | RTLHVSDRQK | AQEKKQLKSK | QQQLLRRLAE | LKRA |