Q1LNG0

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
KEGG Pathway
rme:Rmet_1433
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

715-798 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1LNG0

Entry ID Method Resolution Chain Position Source
AF-Q1LNG0-F1 Predicted AlphaFoldDB

No variants for Q1LNG0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1LNG0

No associated diseases with Q1LNG0

6 regional properties for Q1LNG0

Type Name Position InterPro Accession
domain ACT domain 680 - 760 IPR002912-1
domain ACT domain 787 - 857 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 58 - 110 IPR002934
domain HD/PDEase domain 437 - 593 IPR003607
domain HD domain 441 - 563 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 166 - 304 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDTTPELLLC QRIRDKLKAD KQVLFAEFDA NNQVNPLVTK LRRAVDVALT EAWTGLELPG
70 80 90 100 110 120
DVALVAVGGY GRGELFPHSD VDVLLLLPGE PDAKMAAKLE RFIGLCWDLG LEIGSSVRTV
130 140 150 160 170 180
DDCIRESAAD ITIRTSLLEA RLLIGNKALF KSLQTRYQAD MDAADFFQAK LLEMRQRHAK
190 200 210 220 230 240
YQDTPYALEP NCKESPGGLR DLQVILWMTE AARLGDSWKQ LFERGLLTER EAQELTRNER
250 260 270 280 290 300
LLRTIRARLH LLAGRRQDVL VFDLQTALAE AFGYRQTTNK RASEQLMRRY YWAAKAVTQL
310 320 330 340 350 360
NSVLLLNIEA MLFPSESMVT REINDRFVER QGMLEITSDD LYERNPHAIL ETFLLYERTP
370 380 390 400 410 420
GVKGLSPRTL RGLYNARTVM DASWRNDPVN RRLFLAIVQE PQGITHALRL MNQTSVLGRY
430 440 450 460 470 480
LINFRRIVGQ MQHDLFHVYT VDQHILMVVR NMRRFAIVEH THEFPFCSQL MAGFDRPWVL
490 500 510 520 530 540
WVAALFHDIA KGRGGDHSKL GTVDARRFCK QHGISREDTD LIAWLVEHHL TMSHVAQKQD
550 560 570 580 590 600
LTDPDVVKAF AQVVGNGRYL TALYLLTVAD IRGTSPKVWN AWKGKLLEDL YRITLRVLGG
610 620 630 640 650 660
ARLDTHSLWA QKRDDTIAQL RLKAFDPELA KPLWDKLDMS FFMRQDARDI AWLTRSLFNK
670 680 690 700 710 720
VNSPNPVVKA RISPAGEGLQ VAVYVKDQPD LFARICGYFE RKAFSIQDAK IETTRDGYAL
730 740 750 760 770 780
DTFQITDPGL AGDYRDILTL VEHELGERVR LECPLPDPTQ GRLSRQSRSF PIKPRVDLRP
790 800 810 820 830 840
DERGQYYLLS VSANDRTGLL YAIARVLAKH RVSVHSARIN TLGERVEDVF LVDGSRLAAD
850
NRLQIQLEQD LLDALAI