Q1LLI5

PR
Gene name
rlmD
Protein name
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Names
23S rRNA(m5U1939)-methyltransferase
Species
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
KEGG Pathway
rme:Rmet_2112
EC number
2.1.1.190: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1LLI5

Entry ID Method Resolution Chain Position Source
AF-Q1LLI5-F1 Predicted AlphaFoldDB

No variants for Q1LLI5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1LLI5

No associated diseases with Q1LLI5

2 regional properties for Q1LLI5

Type Name Position InterPro Accession
domain TRAM domain 17 - 81 IPR002792
conserved_site RNA methyltransferase TrmA, conserved site 448 - 458 IPR030391

Functions

Description
EC Number 2.1.1.190 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSQPNPTSH PEAASAASAA SNDPVVKIDS LDMEARGVGR LENEDGTPGK VIFVEGALPG
70 80 90 100 110 120
ETVAYRSYRR KPSYEQAHLV EVKQASVMRV KPGCQHFGVC GGCSMQHLDS RAQLAIKQRV
130 140 150 160 170 180
LEDNLWHLSK VKPDVVFRPI AGPDWGYRYR ARLTVRHVVK KGGVLVGFHE RKSSYVADMT
190 200 210 220 230 240
HCEILPPHVS AMLVPLRELV GGLSIHDRMP QIELAVGAEV TALVLRVLEP LNDADKDLLR
250 260 270 280 290 300
AFADQHQVQF WLQPKGPDTV YPFYPAEQEL AYTLPEFGIR MPFKPTDFTQ VNHQINRVLI
310 320 330 340 350 360
GRALRLLDAK PTDRLLDLFC GIGNFTLPLA TQGASVMGIE GSEVLTTRAL ANAEYNGLAA
370 380 390 400 410 420
KTSFACRNLF EVTAEDIAAL GRFDRWLVDP PREGALAVCK ALAELSQAGS DVLPKRIVYV
430 440 450 460
SCSPATLARD AGLLVHEAGY RLAGAGVVNM FPHTSHVESI AVFERD