Q1KLX8

PR
Gene name
CAMP
Protein name
Cathelicidin antimicrobial peptide
Names
Species
Hylobates moloch (Silvery gibbon)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

35-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1KLX8

Entry ID Method Resolution Chain Position Source
AF-Q1KLX8-F1 Predicted AlphaFoldDB

No variants for Q1KLX8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1KLX8

No associated diseases with Q1KLX8

3 regional properties for Q1KLX8

Type Name Position InterPro Accession
conserved_site Cathelicidin, conserved site 35 - 48 IPR018216-1
conserved_site Cathelicidin, conserved site 79 - 101 IPR018216-2
domain Cathelicidin, antimicrobial peptide, C-terminal 136 - 162 IPR022746

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Vesicle
  • Stored as pro-peptide in granules and phagolysosomes of neutrophils (By similarity)
  • Secreted in sweat onto skin (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
neutrophil activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTQRDGHSL GGWSLMLLLL GLLMPLAIVA QVLSYKEAVL RAIDGINQRS SDANLYRLLD
70 80 90 100 110 120
LDPRPTMDGD PDTPKPVSFT VKETVCPRTT QQSPEDCDFK KDGLVKRCVG TVTLNQARDS
130 140 150 160
FDISCDKDNR RFASLGNFFR KARKKIGEEF KRIVQRIKDF LQHLIPRTEA