Q1K8F7

PR
Gene name
cyt-19
Protein name
ATP-dependent RNA helicase cyt-19, mitochondrial
Names
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU07670
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1K8F7

Entry ID Method Resolution Chain Position Source
AF-Q1K8F7-F1 Predicted AlphaFoldDB

No variants for Q1K8F7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1K8F7

No associated diseases with Q1K8F7

4 regional properties for Q1K8F7

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 239 - 247 IPR000629
domain Helicase, C-terminal 329 - 493 IPR001650
domain DEAD/DEAH box helicase domain 99 - 283 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 94 - 316 IPR014001

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRTSVLRQAG LCRAALAARH LQISSKPSAA LLSQVTRAIA VQSLPSASLP RFYSAEATAQ
70 80 90 100 110 120
SNTAASNGLV TRFADLAALG VHENVVRAIT HGMGYENMTE VQSMTISPAL KGKDIVAQAK
130 140 150 160 170 180
TGTGKTLGFL VPVIQKIITQ DPDLAHRFGG KRARSDDIRA IIISPTRELA EQIGEEARKL
190 200 210 220 230 240
VKGTGIIVQT AVGGTQKNAM LYKTRQQGCH ILVGTPGRLN DLLSDSHSGI DAPRLSTLVL
250 260 270 280 290 300
DEADRMLEVG FNEELRQIIN YLPDRKVLPR QTLLYSATIP KDVVGLARSY IDKNNFEFVQ
310 320 330 340 350 360
TVKADEVLTH DRIPQYIVPC KGFENIYPAM LELIEKALNE SRTNPEALPF KAIVFLPTTA
370 380 390 400 410 420
EVIMANAIFK RLQWKFKHIP KTWDIHSKLT QNARTRAADE FKNARTGILF SSDVTARGMD
430 440 450 460 470 480
FPNVSHVIQT HIPPNREQYI HRLGRTGRAN KPGQGWLIVP DIELHAARSR LPGLPIKRND
490 500 510 520 530 540
ELECASVNAA DSGADKHANF QHILDAASRL PEDLFKDCYS SYLGGALQGI DRQALVYALN
550 560 570 580 590 600
DLAKFGWGLE EPPAVRQSIM KHMGRVQGLR VETREHSMRP MGSGPGHRRD FNSRGPRRQS
610 620
DDPFENALHR AQDLDRRPTR RQQASF