Q1K7M0

PR
Gene name
9G6.250 (NCU04133)
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU04133
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

335-406 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1K7M0

Entry ID Method Resolution Chain Position Source
AF-Q1K7M0-F1 Predicted AlphaFoldDB

No variants for Q1K7M0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1K7M0

No associated diseases with Q1K7M0

No regional properties for Q1K7M0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q1K7M0

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MINPISFRPG PVTFWTTLIY LALLIPIVII NEKTPAAPKT AEPFKGVNLT EAWLDLTTIT
70 80 90 100 110 120
RAYHPYNSKF NEEVRRYLLE KVETILEENG ASWVSDGQMT TVKDGKSAAV TVFDDNVSNS
130 140 150 160 170 180
TFVMGKSNGT TFTRTDSINN AAYFEGTNIL VYIRGKEDDE GEWWEADYAH GMRRNAKGLT
190 200 210 220 230 240
LVNAHYDSVS TGFGATDDGM GVVTALQVLK YFTAPGHQPQ RGIVVMLNNG EEDWLYGAHA
250 260 270 280 290 300
LGQHKLNPFI HTFLNLEGAG AGGRAIVFRA TDREVMAAYA RTSHPFGTVI ASDAFGLGFI
310 320 330 340 350 360
SSGTDYSVLV DAYGQRGIDL AFFKPRARYH TNQDDTRHTS KGSLWHMLSA AIHTTKQFSG
370 380 390 400 410 420
DTGNTFIGQR PDKAHGKVAN GRSSNGVWFD LFGKSFVLFG LRGMFAWSLT LLIATPLVLV
430 440 450 460 470 480
GITWLLRNLD KDYFFTSTVK TKEHPEYEAV PIGGWKGFFR FPFALGVAVF FTISSALLMN
490 500 510 520 530 540
KVNPLIVYSS RYSVWVMMVS IFYFSFWMIM RGANFVRPSA LHRGYANLWL FVFGWIVLVA
550 560 570 580 590 600
VTALEDRRRI AAGYIFVFLE SAIFLSCLIS FVELLAVPRK SSYALQVQED YDGQEHDHNG
610 620 630 640 650 660
YQGFRDSTDE PSLRARAESS ASAASPPSPT VAQEPSKSKA PAGTTNGLST APSVAAHSSQ
670 680 690 700 710 720
PQPAPTTPIP GRSSGAPSTA SRDENESEDD DEPTERTPLV GGNGTNDRGR TTFATTYRRS
730 740 750 760 770 780
ITALVHGARK MEEDGEPYDH EQEWSGHLPS WAWFFQFLLL GPFMIILAAQ TGLMLTDAVY
790 800 810 820 830 840
QTGSDGSKLI TPYLIIFVFT VLLILPLTPF IHRVTHHIPV FLLVVFIVTL TYNLIAFPFS
850 860 870 880 890 900
ANNRYKTFFG QYIDVATGDN KVCYTGIEEY VRPIIAELPS ASGREVTCGK SLRRGSTIST
910 920 930 940 950 960
CCFDGSAVPP KLGSEDDNGL PEDSYADLIT INATRSTKRG DSSRTTARIE ITADNTKSCF
970 980 990 1000 1010 1020
LQFKKPVSAL AIENGSGWDD RFGQYPEDGV GLVRLWHREF GKTWVVNAEW KGSETRKEYD
1030 1040 1050 1060 1070
ENDGTVICMW SDANTPGTIP ALDEALQFVP SWAAVTKFSE GLVEGRKAFK IV