Q1JHV6

PR
Gene name
tuf
Protein name
Elongation factor Tu
Names
EF-Tu
Species
Streptococcus pyogenes serotype M2 (strain MGAS10270)
KEGG Pathway
sph:MGAS10270_Spy0502
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1JHV6

Entry ID Method Resolution Chain Position Source
AF-Q1JHV6-F1 Predicted AlphaFoldDB

No variants for Q1JHV6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1JHV6

No associated diseases with Q1JHV6

7 regional properties for Q1JHV6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 10 - 207 IPR000795
domain Translation elongation factor EFTu/EF1A, C-terminal 302 - 396 IPR004160
domain Translation elongation factor EFTu-like, domain 2 228 - 297 IPR004161
domain Small GTP-binding protein domain 13 - 149 IPR005225
conserved_site Tr-type G domain, conserved site 54 - 69 IPR031157
domain Elongation factor Tu, domain 2 215 - 301 IPR033720
domain Elongation factor Tu (EF-Tu), GTP-binding domain 11 - 206 IPR041709

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PSSVNQPKDY ASIDAAPEER
70 80 90 100 110 120
ERGITINTAH VEYETATRHY AHIDAPGHAD YVKNMITGAA QMDGAILVVA STDGPMPQTR
130 140 150 160 170 180
EHILLSRQVG VKHLIVFMNK VDLVDDEELL ELVEMEIRDL LSEYDFPGDD LPVIQGSALK
190 200 210 220 230 240
ALEGDTKFED IIMELMDTVD SYIPEPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGTV
250 260 270 280 290 300
RVNDEIEIVG IKEETKKAVV TGVEMFRKQL DEGLAGDNVG ILLRGVQRDE IERGQVIAKP
310 320 330 340 350 360
GSINPHTKFK GEVYILSKDE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA GTEMVMPGDN
370 380 390
VTINVELIHP IAVEQGTTFS IREGGRTVGS GIVSEIEA