Q1JAC1

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Streptococcus pyogenes serotype M12 (strain MGAS2096)
KEGG Pathway
spj:MGAS2096_Spy1435
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-232 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1JAC1

Entry ID Method Resolution Chain Position Source
AF-Q1JAC1-F1 Predicted AlphaFoldDB

No variants for Q1JAC1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1JAC1

No associated diseases with Q1JAC1

6 regional properties for Q1JAC1

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 454 - 623 IPR000795
domain Small GTP-binding protein domain 457 - 613 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 374 - 425 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 729 - 844 IPR023115
domain Translation initiation factor IF-2, domain II 629 - 724 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKRLHEIA KEIGKSSKEV VEHAKYLGLD VKSHASSVEE ADAKKIISSF SKASKPDVTA
70 80 90 100 110 120
SQTVKPKEVA QPSVTVVKET GSEHVEKTQV SKPKSRNFKA EREARAKEQA ARKQANGSSH
130 140 150 160 170 180
RSQERRGGYR QPNNHQTNEQ GDKRITHRSQ GDTNDKRIER KASNVSPRHD NHQLVGDRNR
190 200 210 220 230 240
SFAKENHKNG RFTNQKKQGR QEPQSKSPKI DFKARAAALK AEQNAEYSRQ SETRFRAQQE
250 260 270 280 290 300
AKRLAELARQ EAKEAALKAQ AEEMSHREAA LKSIEEAETK LKSSNISAKS TADNRRKKQA
310 320 330 340 350 360
RPEKNRELTH HSQEGQKKNK KSWNSQNQVR NQKNSNWNKN KKTKKGKNVK NTNTAPKPVT
370 380 390 400 410 420
ERKFHELPKE FEYTEGMTVA EIAKRIKREP AEIVKKLFMM GVMATQNQSL DGDTIELLMV
430 440 450 460 470 480
DYGIEAKAKV EVDDADIERF FEDENYLNPE NIVERAPVVT IMGHVDHGKT TLLDTLRNSR
490 500 510 520 530 540
VATGEAGGIT QHIGAYQIEE AGKKITFLDT PGHAAFTSMR ARGASVTDIT ILIVAADDGV
550 560 570 580 590 600
MPQTIEAINH SKAAGVPIIV AINKIDKPGA NPERVIAELA EYGIISTAWG GECEFVEISA
610 620 630 640 650 660
KFNKNIDELL ETVLLVAEVE ELKADPTVRA IGTVIEARLD KGKGAIATLL VQQGTLHVQD
670 680 690 700 710 720
PIVVGNTFGR VRAMVNDLGR RVKSAEPSTP VSITGLNETP MAGDHFAVYA DEKAARAAGE
730 740 750 760 770 780
ERSKRALLKQ RQNTQRVSLD NLFDTLKAGE IKTVNVIIKA DVQGSVEALA ASLVKIEVEG
790 800 810 820 830 840
VRVNVVHSAV GAINESDVTL AEASNAVIIG FNVRPTPQAR QQADTDDVEI RLHSIIYKVI
850 860 870 880 890 900
EEVEEAMKGK LDPVYQEKIL GEAIIRETFK VSKVGTIGGF MVINGKVTRD SSVRVIRDSV
910 920 930 940 950
VIFDGKLASL KHYKDDVKEV GNAQEGGLMI ENFNDLKVDD TIEAYIMEEI VRK