Q1IU72
Gene name |
kdsB |
Protein name |
3-deoxy-manno-octulosonate cytidylyltransferase |
Names |
CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase |
Species |
Koribacter versatilis (strain Ellin345) |
KEGG Pathway |
aba:Acid345_0573 |
EC number |
2.7.7.38: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1IU72
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1IU72-F1 | Predicted | AlphaFoldDB |
No variants for Q1IU72
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q1IU72 | |||||
No associated diseases with Q1IU72
5 regional properties for Q1IU72
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminoacyl-tRNA synthetase, class II (D/K/N) | 164 - 507 | IPR004364 |
| domain | OB-fold nucleic acid binding domain, AA-tRNA synthetase-type | 69 - 147 | IPR004365 |
| domain | Aminoacyl-tRNA synthetase, class II | 185 - 509 | IPR006195 |
| domain | Lysyl-tRNA synthetase, class II, C-terminal | 178 - 509 | IPR018149 |
| domain | Lysine-tRNA ligase, class II, N-terminal | 68 - 175 | IPR044136 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.38 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-deoxy-manno-octulosonate cytidylyltransferase activity | Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate. |
| lipopolysaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPPRVSRFNL | PEPAPRVETG | TVKAIAVIPA | RIASTRLPRK | ILREIDGRTM | LDRVYNAAKG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| APMLADVIVA | TDSQEIMDVC | NRHGWNARLT | SDQHRSGTDR | VHEVAQTVAA | DVYVNVQGDE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PLARPEHLNT | LLELMRDETV | QVGTLKTPCG | KEDVANPNAV | KVVTDKTGRA | LYFSRSTVPY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DRDNRGDIAY | FKHLGFYAYR | KPTLDRFCGW | PESSLERSER | LEQLRFLENG | VDIYVAETPY |
| 250 | 260 | ||||
| DTIGVDTEAD | LKRVEEILRS | RN |