Q1IHQ3

PR
Gene name
asnS
Protein name
Asparagine--tRNA ligase
Names
Asparaginyl-tRNA synthetase, AsnRS
Species
Koribacter versatilis (strain Ellin345)
KEGG Pathway
aba:Acid345_4597
EC number
6.1.1.22: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

49-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1IHQ3

Entry ID Method Resolution Chain Position Source
AF-Q1IHQ3-F1 Predicted AlphaFoldDB

No variants for Q1IHQ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1IHQ3

No associated diseases with Q1IHQ3

3 regional properties for Q1IHQ3

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 118 - 436 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 20 - 98 IPR004365
domain Aminoacyl-tRNA synthetase, class II 137 - 432 IPR006195

Functions

Description
EC Number 6.1.1.22 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
asparagine-tRNA ligase activity Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
nucleic acid binding Binding to a nucleic acid.

1 GO annotations of biological process

Name Definition
asparaginyl-tRNA aminoacylation The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEQAPVSTIH EIGKHDGQSV TIKGWLYNLR ESGKLLFPIF RDGTGLLQGV LFKKNVSPEL
70 80 90 100 110 120
FDLVKNLTQE SSVIVTGNVR AEQRAPGGYE MDVTALEVVQ RVPENEPYPI TPKEHGIEFL
130 140 150 160 170 180
MEHRHLWVRS QRQAAILRIR GEIVRSAHEF FDKQGFTLTE PPILTPAACE GTSTLFPVDY
190 200 210 220 230 240
FGDPAFLTQS GQLYIEATAM ALGKVYSFGP TFRAEKSKTR RHLTEFWMVE PEVAFAELDD
250 260 270 280 290 300
IMKLAEDFIT HIVKSVLERR RDDLKTIERD LSKLENIDTP FPRISYDEAV QMLQEGHAKG
310 320 330 340 350 360
ELESRFEWGG DLGSPDETYI SSKFDRPVMI HRYPVEVKAF YMEPDPNNSK VALCVDVLAP
370 380 390 400 410 420
EGYGEVIGGS QRMGSYEKLL ARIHEHQLPE ESFKWYLDLR KFGGVPHSGF GMGIERAVAW
430 440
ICGLDHVRET IPFARTLHRI YP