Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q1GXD6

Entry ID Method Resolution Chain Position Source
AF-Q1GXD6-F1 Predicted AlphaFoldDB

No variants for Q1GXD6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1GXD6

No associated diseases with Q1GXD6

6 regional properties for Q1GXD6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 407 - 576 IPR000795
domain Small GTP-binding protein domain 410 - 566 IPR005225
domain Translation initiation factor IF-2, N-terminal 331 - 381 IPR006847
domain Initiation factor 2 associated domain, bacterial 60 - 98 IPR013575
domain Translation initiation factor IF- 2, domain 3 683 - 797 IPR023115
domain Translation initiation factor IF-2, domain II 582 - 676 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQSSVAQFA SELGLPAELL LEQLRGAGVN KTAYDDVLTE QDKTSLLEYL RKEHGVQEPK
70 80 90 100 110 120
NKITLTRKQV TEIKKSDSSG KARTIQVEVR KKRVLVRRDP ALEPVVAEES AEIAPAAVID
130 140 150 160 170 180
EPTLQAAPVV LPEPEPVVEA VPEPVAVEQE LESEPEPTVA PAEPEAGEVA VAVDEKPTAD
190 200 210 220 230 240
ARPKLTAREL LGAEELALRE REAKRQAALM AIQAEELRKK QELAQRRQEE AKRAAEAAAN
250 260 270 280 290 300
KLSEGTLHKP VAKEAPKPEE KNAKKTGKSG GKDWNDSDGK KRGGVKGRSD AGVAGQGWRA
310 320 330 340 350 360
KGSKSKSKNN ENQQHAFTAP TEPIVHDVLV PETITVGDLA HKMAVKASEV IKTLMKMGMM
370 380 390 400 410 420
VTINQVLDQE TAIIIVEEMG HNAKAAASND PEAFLDEAEH AEAVQEPRPP VVTVMGHVDH
430 440 450 460 470 480
GKTSLLDYIR RSRVASGEAG GITQHIGAYH VETPRGMVTF LDTPGHEAFT AMRARGAKAT
490 500 510 520 530 540
DVVILVVAAD DGVMPQTIEA VHHAKAANVP IVVAVNKIDK PEANPERVKQ ELVSHEVVPE
550 560 570 580 590 600
DWGGDTMFVE VSAKTGAGID NLLEAVLLQA EVLELKAPKN IPAKGLVIEG RLDKGRGPVS
610 620 630 640 650 660
TILVQSGTLQ RGDMILAGTA YGRVRAMLDE SGRDVKEAGP SIPVEILGLS DVPSAGEEVI
670 680 690 700 710 720
VLNDERKARE IALFRQGKFR DVKLAKQQAA KLESMFEQMG EGEVKVLHLI IKSDVQGSYE
730 740 750 760 770 780
ALSTSLQKLS TDEVKVNIIH TGVGAISESD VNLAAASKAV LIGFNVRADA GARKLIESTG
790 800 810 820 830 840
VDVRYYNIIY EAVDEVKAAL GGMLSPEQKE NVIGTVEIRE VFRISKVGSV AGCYVQDGVV
850 860 870 880 890 900
RRNSKVRLIR DNVVIHTGEL DSLKRFKDDV KEVKSNFECG LSLKNYNEIE VGDILEVFEV
VEVARTL