Q1GWP7

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
KEGG Pathway
sal:Sala_0201
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-43 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1GWP7

Entry ID Method Resolution Chain Position Source
AF-Q1GWP7-F1 Predicted AlphaFoldDB

No variants for Q1GWP7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1GWP7

No associated diseases with Q1GWP7

3 regional properties for Q1GWP7

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 278 - 287 IPR020557
domain Fumarate lyase, N-terminal 9 - 303 IPR022761
domain Argininosuccinate lyase, C-terminal 366 - 433 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANTPDKSSM WGGRFGGGPA AIMQEINASI PIDKRLWEED IAASRAHAAM LGACRIISAD
70 80 90 100 110 120
DAAAIDRGLA QIAEEFAENG VPVDLSLEDI HMTVEARLKE LIGEPAGRLH TARSRNDQVA
130 140 150 160 170 180
TDFRLWTRTA CERIDAGLAA LQSALLQRAD EHADSIMPGF THLQVAQPVT LGHHLLAYVE
190 200 210 220 230 240
MARRDRGRFA DARRRLNESP LGAAALAGTG FPVDRDATAA ALGFDRPMAN SIDAVSDRDF
250 260 270 280 290 300
ALEFCAAAAI AAIHLSRLAE EIVIWASQPF GFVALPDAWS TGSSIMPQKR NPDAAELVRG
310 320 330 340 350 360
RAGLLLGAFQ RLAVIVKGLP LTYSKDLQDD KETLFGAFDA LALSLAAMTG MVETLSFRTD
370 380 390 400 410 420
RMRALAASGY STATDLADWL VREAGLPFRE AHHVVGACVR RAEELGVELP ALPAADAAAI
430 440 450 460
HAAVTPDVLA ALTVEASVAS RMSYGGTAPE RVRQAIAAAR AAAAQGQD