Q1GV29

PR
Gene name
astD
Protein name
N-succinylglutamate 5-semialdehyde dehydrogenase
Names
Succinylglutamic semialdehyde dehydrogenase, SGSD
Species
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
KEGG Pathway
sal:Sala_0773
EC number
1.2.1.71: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

388-481 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1GV29

Entry ID Method Resolution Chain Position Source
AF-Q1GV29-F1 Predicted AlphaFoldDB

No variants for Q1GV29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1GV29

No associated diseases with Q1GV29

3 regional properties for Q1GV29

Type Name Position InterPro Accession
domain Aldehyde dehydrogenase domain 6 - 444 IPR015590
conserved_site Aldehyde dehydrogenase, cysteine active site 256 - 267 IPR016160
conserved_site Aldehyde dehydrogenase, glutamic acid active site 228 - 235 IPR029510

Functions

Description
EC Number 1.2.1.71 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
succinylglutamate-semialdehyde dehydrogenase activity Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.

2 GO annotations of biological process

Name Definition
arginine catabolic process to glutamate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
arginine catabolic process to succinate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEELLSFEP ATGEQLWRGK VSDVDAEVEI ARRAWPEWAA KPVTFRTETL RRFADRVKAE
70 80 90 100 110 120
SEAFADLIAR ETGKPLWEAR TEVESVANKV DISVKAYAER TPNRRIEGAM GLRSAVRHKP
130 140 150 160 170 180
HGALAVLGPY NFPAHLPNGH IVPALIAGNS VVFKPSEKTP AVGAKLVELL HSAGVPQEVL
190 200 210 220 230 240
RLVVGGPDTG KALAAHPGID GLLFTGSART GLALNRQFAG QPGKMLALEM GGNNPIVAWD
250 260 270 280 290 300
TADIRTAAIL IVQSAFLSAG QRCSNARRLI VKDSLADALI AEVRELANRL IVDHPHADPA
310 320 330 340 350 360
PYMGPVIDNE AADGLTESFL VLMSNGGQVI RHMTRPVAGR PFLTPGIIDV TTMAERPDVE
370 380 390 400 410 420
LFGPLLQVIR VETFEAAIAE ANNTAFGLSA ALIGGTPQLY DQFWANARAG VINWNRPTNG
430 440 450 460 470 480
ASSAAPFGGV GLSGNHRPSA FYAADYCAYP VASAESDALR ASIGVGLRDP EGSQLVTKKY
L