Q1GLE1
Gene name |
TM1040_3556 |
Protein name |
dTTP/UTP pyrophosphatase |
Names |
dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase |
Species |
Ruegeria sp (strain TM1040) (Silicibacter sp) |
KEGG Pathway |
sit:TM1040_3556 |
EC number |
3.6.1.9: In phosphorus-containing anhydrides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1GLE1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1GLE1-F1 | Predicted | AlphaFoldDB |
No variants for Q1GLE1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q1GLE1 | |||||
No associated diseases with Q1GLE1
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.1.9 | In phosphorus-containing anhydrides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| dTTP diphosphatase activity | Catalysis of the reaction: dTTP + H2O = dTMP + H+ + diphosphate. |
| UTP diphosphatase activity | Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| nucleotide metabolic process | The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAFILGSGSP | RRLELLAQLG | VTPDDIRPPD | IDETPQKGEL | PRDYCARVTR | QKAEAVTSNP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EDLVLCADTT | VVLGRRIMGK | PRDAGEAAEF | LLALSGRRHR | VITSVALRKQ | DRLWQKDVVS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QVKMKRLSDE | ELNAYLATGD | WEGKAGGYAI | QGPAGALIPW | ISGSFTAIVG | LPLAETATLL |
| 190 | |||||
| QTAGYPLYKD | TAS |