Q1EB85

PR
Gene name
DBP5 (CIMG_00178)
Protein name
ATP-dependent RNA helicase DBP5
Names
Species
Coccidioides immitis (strain RS) (Valley fever fungus)
KEGG Pathway
cim:CIMG_00178
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1EB85

Entry ID Method Resolution Chain Position Source
AF-Q1EB85-F1 Predicted AlphaFoldDB

No variants for Q1EB85

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1EB85

No associated diseases with Q1EB85

5 regional properties for Q1EB85

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 241 - 249 IPR000629
domain Helicase, C-terminal 307 - 488 IPR001650
domain DEAD/DEAH box helicase domain 117 - 282 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 111 - 311 IPR014001
domain RNA helicase, DEAD-box type, Q motif 92 - 120 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
  • Nucleus, nuclear pore complex
  • Nucleus membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Nuclear pore complex cytoplasmic fibrils
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nuclear pore A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
mRNA transport The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASENTTETP SVPAGGPLAA RISRPEGDAN PPSTEAEKPA AEDDSGKGPS IPQVDGASED
70 80 90 100 110 120
QRGSELQDSE FDVNVKLSDL QADPNNPLYS IKSFEELGLA EPIQMGLSKM NFRRPSKIQE
130 140 150 160 170 180
RALPLLMANP PTNMIAQSQS GTGKTAAFVL NILSRLELTP EKQKSPQALV LAPSRELARQ
190 200 210 220 230 240
IVGVIQAMGT FVEGLFVATA VPMEMNRNQR VEASIVVGTP GTVQDLIKKR LFNTQHLRVL
250 260 270 280 290 300
VLDEADNMLD QQGLGDQCIR VKSLLPRTIQ VVLFSATFPD FVVRYAHKFA PNSNQLTLKH
310 320 330 340 350 360
EELTVEGIKQ LYLDCESDEH KYEILVKFYG LLTIGSSIIF VKTRASAAEI ERRMVAEGHT
370 380 390 400 410 420
VVSLTGGIEG QKRDEIIDRF RNGTAKVLIT TNVLARGIDV STVSMVINYD IPELHLPGAA
430 440 450 460 470 480
RRMADAQTYL HRIGRTGRFG RVGVAVSFVS NQEEWQMLQD IQKYFSTNIE RVDTRDWDDV
490
EKKVKKIIKP SAVAR