Q1E4T3

PR
Gene name
MDM34
Protein name
Mitochondrial distribution and morphology protein 34
Names
Species
Coccidioides immitis (strain RS) (Valley fever fungus)
KEGG Pathway
cim:CIMG_02430
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

397-543 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1E4T3

Entry ID Method Resolution Chain Position Source
AF-Q1E4T3-F1 Predicted AlphaFoldDB

No variants for Q1E4T3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1E4T3

No associated diseases with Q1E4T3

1 regional properties for Q1E4T3

Type Name Position InterPro Accession
domain Synaptotagmin-like mitochondrial-lipid-binding domain 1 - 195 IPR031468

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion outer membrane ; Multi-pass membrane protein
  • The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions
  • These foci are often found next to mtDNA nucleoids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ERMES complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
integral component of mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

2 GO annotations of biological process

Name Definition
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
mitochondrial genome maintenance The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFNFNWSPL MADAGFYTRA QDLLTTALNK SPKPPIIVDD IVVTELNLGS IPPELEILEI
70 80 90 100 110 120
GDLAEDRFRG IFKMSYSGDA FLTLKTRVQA NPLNTYLITR PAYASPKPLA AASGLTIPLQ
130 140 150 160 170 180
ITLSNFRLSG FVILVFSKQK GITVVFRNDP LESLKVSSTF DSIPSVRDYL QREIEGQLRI
190 200 210 220 230 240
LFMDELPAII HRLSLRLWVP EYRGLDAEAR ESPAASASGP GEDPLLSPPK DPVDASGNLL
250 260 270 280 290 300
SSADIASLSL DSGVEMHSLF SQKNLLRLAA LTNSQRTLSL FTPSIREVVF RAWTGCADQG
310 320 330 340 350 360
EGAASGVVSP GSPVLSRTHS HISSPLSSLQ DASSVLSLQN RSTTPGSSFS GYGLSLGAGR
370 380 390 400 410 420
HSKTRPTRKR KKRVVDLRKH NKPADAESVS ADSTFTESTT PPTVFSSSVI QEEANDDPVT
430 440 450 460 470 480
PPMSPETTMR IPNRQHRFST SEDKGKLRAS VAQQLTYTQP SHSTLHAQRA NHCPMIPLSA
490 500 510 520 530 540
DGAKTSSQQQ PISHGSYLAP REKSHEASSA YESNANRSIT DAVPNSSILE QAWMMKMANE
550 560 570
IARRIQEGKF AANNNYPGAW EQARARTPPP AYGQ