Q1DRB6

PR
Gene name
ERB1
Protein name
Ribosome biogenesis protein ERB1
Names
Eukaryotic ribosome biogenesis protein 1
Species
Coccidioides immitis (strain RS) (Valley fever fungus)
KEGG Pathway
cim:CIMG_07147
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-228 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1DRB6

Entry ID Method Resolution Chain Position Source
AF-Q1DRB6-F1 Predicted AlphaFoldDB

No variants for Q1DRB6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1DRB6

No associated diseases with Q1DRB6

8 regional properties for Q1DRB6

Type Name Position InterPro Accession
repeat WD40 repeat 401 - 449 IPR001680-1
repeat WD40 repeat 527 - 569 IPR001680-2
repeat WD40 repeat 572 - 610 IPR001680-3
repeat WD40 repeat 613 - 652 IPR001680-4
repeat WD40 repeat 656 - 704 IPR001680-5
repeat WD40 repeat 707 - 751 IPR001680-6
domain BOP1, N-terminal domain 144 - 401 IPR012953
conserved_site WD40 repeat, conserved site 427 - 441 IPR019775

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Nucleus, nucleoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

1 GO annotations of molecular function

Name Definition
ribonucleoprotein complex binding Binding to a complex of RNA and protein.

2 GO annotations of biological process

Name Definition
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTASSGGYQG WERRNNNIPE TVGILFLQVR AVSSGKKAAQ CRETAPTAGL SESSRPRLFA
70 80 90 100 110 120
MDYSKGSKKR KAITKDVDED PSVVSGDEYD LEALDRNDSD SSADASDSEI ELIGDFSSDD
130 140 150 160 170 180
GEDDDGEDDD ELDSDEVPSD TEPFARVKSG NIATGLDGSL DGESNDLSDD NEPNYRIEKD
190 200 210 220 230 240
ANGNDRYIYP EINPDDNSEY SEVDEEANTI GDIPLSFYDQ YPHIGYNING KKILRPAKGQ
250 260 270 280 290 300
ALDALLDSIE IPKGWTGLTD PSTGKPLQLS QEELELLRKV QMNEITQDGY DPYQPTIEYF
310 320 330 340 350 360
TSKQEIMPLS AAPEPKRRFI PSKHEAKRVM KIVKAIREGR ILPYKPPEEE DATQEGIQTY
370 380 390 400 410 420
DLWADESPRP DHPMNIPAPK LPPPGYEESY HPPPEYLPDK KEKEEWENQD EEDREREYLP
430 440 450 460 470 480
TDYSTLRKVP GYERFVKEKF ERCLDLYLAP RVRRSKLNID PESLLPKLPS PEELKPFPTT
490 500 510 520 530 540
CATLFRGHRG RVRSLAIDPT GVWLASGGDD GTVRVWELLT GRQLWSVKLS DEDAVNVVRW
550 560 570 580 590 600
RPGKEAVVLA ASVGDSIYLA VPDVVNLELE AASLEVIDAG WGYATSTGTS TTKKTSPVQW
610 620 630 640 650 660
TRPASSLADS GVYAVIPLGY IAKSISWHRR GDYFVTVCPG TSTPASVAIA IHTLSKHLTQ
670 680 690 700 710 720
YPFRRRLKGG GSPQVAHFHP SKPILFVANQ RSIRAYDLSR QTLVKILRPG ARWISSFDIH
730 740 750 760 770 780
PTSSSTSGGD NLIVGSYDRR LLWHDVDLSD RPYKTLRYHQ KAIRAVKYHP HYPLFADTSD
790 800 810 820 830 840
DGSLQIFHGS VTGDLLSNAN IVPLKVLKGH KVTGDLGVLD LDWHPREAWC VSAGADGTCR
LWM