Q1DDB7

PR
Gene name
pyrG
Protein name
CTP synthase
Names
Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase
Species
Myxococcus xanthus (strain DK1622)
KEGG Pathway
mxa:MXAN_1096
EC number
6.3.4.2: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

395-489 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1DDB7

Entry ID Method Resolution Chain Position Source
AF-Q1DDB7-F1 Predicted AlphaFoldDB

No variants for Q1DDB7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1DDB7

No associated diseases with Q1DDB7

3 regional properties for Q1DDB7

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 7 - 269 IPR017456
domain Glutamine amidotransferase 305 - 529 IPR017926
domain CTP synthase GATase domain 294 - 528 IPR033828

Functions

Description
EC Number 6.3.4.2 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CTP synthase activity Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
glutaminase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRSKKTKFIF VTGGVVSSLG KGLASASIGA LLENRGLAVT LIKLDPYINV DPGTMSPFQH
70 80 90 100 110 120
GEVFVTEDGG ETDMDLGHYE RFTNARMSRL NNFTSGRIYH AVIMKERRGE YLGKTVQVIP
130 140 150 160 170 180
HVTDEIKSSI RQAAQDADVV IVEVGGTVGD IESLPFLEAI RQMRYDVGNE NVVYVHLTLL
190 200 210 220 230 240
PYIGAAGEVK TKPTQHSVMK LREIGIQPDF LVCRTDREVP RELKDKIAMF CNVDTRSVFT
250 260 270 280 290 300
SPDVRSTYEL PLELHRQGLD ERLAEVLNIW SRAPHLERWE NIIRKVYEPA RGQVRIAIVG
310 320 330 340 350 360
KYVNLTESYK SLNEALLHGG IANDVKVNLH FVDSQEVEEQ GAEKLLAGVD AILVPGGFGV
370 380 390 400 410 420
RGTEGKIAAV RYAREKKVPF FGICLGLQMA VVEFSRGVLG LSSANSLEFN EHTPHPVVTL
430 440 450 460 470 480
MESQVKVQDK GGTMRLGSYA CALKPGSLAH QLYGQDTIQE RHRHRYEVNN AYRSKLQEAG
490 500 510 520 530 540
LVISGSNPEL NLVEMIELAD HPYFIGCQFH PEFKSKPFAP HPLFSGFIRA ALAQRDANAA
AGKVTE