Q1CAS3

PR
Gene name
mutH
Protein name
DNA mismatch repair protein MutH
Names
Methyl-directed mismatch repair protein
Species
Yersinia pestis bv Antiqua (strain Antiqua)
KEGG Pathway
ypa:YPA_0481
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1CAS3

Entry ID Method Resolution Chain Position Source
AF-Q1CAS3-F1 Predicted AlphaFoldDB

No variants for Q1CAS3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1CAS3

No associated diseases with Q1CAS3

3 regional properties for Q1CAS3

Type Name Position InterPro Accession
domain DNA mismatch repair protein, S5 domain 2-like 209 - 327 IPR013507
conserved_site DNA mismatch repair, conserved site 94 - 100 IPR014762
domain MutL, C-terminal, dimerisation 485 - 628 IPR014790

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

2 GO annotations of biological process

Name Definition
DNA modification The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVYSLPPAP PSDEHQLFQR AQALSGFTLG ELATRAQWVI PADLKRVKGW VGMLLEFYLG
70 80 90 100 110 120
ASAGSKPEQD FADIGIELKT IPISAQGKPL ETTFVCVAPL TGNSGVTWES SHVRHKLARV
130 140 150 160 170 180
LWVPVEGERH IPLAERRVGA PLLWSPNVEE EELLRRDWEE LMDLIVLGKV ESITARHGQV
190 200 210 220
LQLRPKAANS RALTEAIGEF GQPIMTLPRG FYLKKTLTAP MLARHFLL