Q1BIC1

PR
Gene name
Bcen_5766
Protein name
NAD(P)H dehydrogenase (quinone)
Names
Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO
Species
Burkholderia cenocepacia (strain AU 1054)
KEGG Pathway
bcn:Bcen_5766
EC number
1.6.5.2: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

134-200 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1BIC1

Entry ID Method Resolution Chain Position Source
AF-Q1BIC1-F1 Predicted AlphaFoldDB

No variants for Q1BIC1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1BIC1

No associated diseases with Q1BIC1

12 regional properties for Q1BIC1

Type Name Position InterPro Accession
domain Bromodomain 1333 - 1441 IPR001487
domain Zinc finger, RING-type 1187 - 1232 IPR001841
domain Zinc finger, PHD-type 1186 - 1232 IPR001965
domain WSTF/Acf1/Cbp146 20 - 126 IPR013136
conserved_site Bromodomain, conserved site 1357 - 1414 IPR018359
domain DDT domain 605 - 669 IPR018501
conserved_site Zinc finger, PHD-type, conserved site 1187 - 1231 IPR019786
domain Zinc finger, PHD-finger 1184 - 1234 IPR019787
domain WHIM2 domain 900 - 1024 IPR028941
domain WHIM1 domain 728 - 768 IPR028942
domain Tyrosine-protein kinase BAZ1B, bromodomain 1340 - 1436 IPR037375
domain Tyrosine-protein kinase BAZ1B, PHD finger 1186 - 1231 IPR047256

Functions

Description
EC Number 1.6.5.2 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NADH dehydrogenase (quinone) activity Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
NADPH dehydrogenase (quinone) activity Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKVLVLYYS SYGHIETMAQ HIVEGAKSVP GVEVTLKRVP ETIPVDQARA IGVKVDQAAP
70 80 90 100 110 120
VATVDELADY DAIIFGTPTR FGNMAGQMRT FLDQTGGLWM KGALVGKIGS VFASTGTQHG
130 140 150 160 170 180
GQETTITSFH TTLLHHGMVI VGVPYACSGL VNMSEITGGT PYGATTLAGA DGSRQPSANE
190
LDIARYQGKH VAELASKLAS