Q1B551

PR
Gene name
atpA
Protein name
ATP synthase subunit alpha
Names
ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha
Species
Mycobacterium sp (strain MCS)
KEGG Pathway
mmc:Mmcs_3878
EC number
7.1.2.2: Hydron translocation linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

489-548 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1B551

Entry ID Method Resolution Chain Position Source
AF-Q1B551-F1 Predicted AlphaFoldDB

No variants for Q1B551

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1B551

No associated diseases with Q1B551

6 regional properties for Q1B551

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 121 - 552 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 20 - 103 IPR004365
domain Aminoacyl-tRNA synthetase, class II 141 - 550 IPR006195
domain GAD domain 314 - 400 IPR029351
domain Aspartate-tRNA ligase, type 1, anticodon recognition domain 3 - 137 IPR047089
domain Aspartate-tRNA ligase, type 1, core domain 141 - 554 IPR047090

Functions

Description
EC Number 7.1.2.2 Hydron translocation linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
proton-transporting ATP synthase complex, catalytic core F(1) The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
proton-transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAELTISAAD IQGAIEDYVA NFATDTEREE IGTVIDAGDG IAHVEGLPSV MTQELLEFPG
70 80 90 100 110 120
GVLGVALNLD EHSIGAVILG DFEKIEEGQQ VKRTGEVLSV PVGDGYLGRV VNPLGQPIDG
130 140 150 160 170 180
RGEIETTDRR ALELQAPSVV QRQGVSEPLQ TGIKAIDSQT PIGRGQRQLI IGDRKTGKTA
190 200 210 220 230 240
VCVDTILNQR QNWETGDPNQ QVRCVYVAIG QKGTTIASVR RTLEEGGAMD YTTIVAAPAS
250 260 270 280 290 300
DSAGFKWLAP YTGSAIAQHW MYDGKHVLIV FDDLTKHAEA YRAISLLLRR PPGREAFPGD
310 320 330 340 350 360
VFYLHSRLLE RCAKLSDELG GGSMTGLPLI ETKANDISAY IPTNVISITD GQCFLETDLF
370 380 390 400 410 420
NQGVRPAINV GVSVSRVGGA AQIKAMKEVA GSLRLDLSQY RELESFAAFA SDLDATSKAQ
430 440 450 460 470 480
LDRGARLVEL LKQPQNSPMP VEEQVVAIFL GTRGHLDTVP VEDVQRFEQE LLEHVRSSKE
490 500 510 520 530 540
EIFTEIRESK KLSDELEKTL TDVVNEFKKG FETTSGESVV PDENVEAMSE DDVEKESVKV
RKPAPKKK