Q1A268

PR
Gene name
gag
Protein name
Gag polyprotein
Names
Pr55Gag
Species
Simian immunodeficiency virus (isolate MB66) (SIV-cpz) (Chimpanzee immunodeficiency virus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

74-153 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q1A268

Entry ID Method Resolution Chain Position Source

No variants for Q1A268

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1A268

No associated diseases with Q1A268

No regional properties for Q1A268

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q1A268

Functions

Description
EC Number
Subcellular Localization
  • [Matrix protein p17]: Virion
  • Host nucleus
  • Host cytoplasm
  • Host cell membrane ; Lipid-anchor
  • Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome
  • During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
host cell cytoplasm The cytoplasm of a host cell.
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell plasma membrane The plasma membrane surrounding a host cell.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.

3 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural molecule activity The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
viral budding via host ESCRT complex Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGARASVLTG GKLDRWEKIY LRPGGKKKYM MKHLVWASRE LERFACNPSL METTEGCKQL
70 80 90 100 110 120
LQQLEPALKT GSEGLRSLFN TIVVLWCVHQ GIPVKDTKEA LDQLQEAQQK GKQEVAAATA
130 140 150 160 170 180
DGTSTVSRNF PIVANAQGQM VHQPISPRTL NAWVKVVEEK AFSPEVIPMF MALSEGATPQ
190 200 210 220 230 240
DLNTMLNTVG GHQAAMQMLK EVINEEAAEW DRLHPVHAGP VPPGQMREPR GSDIAGTTST
250 260 270 280 290 300
IQEQVGWMTS NPPIPVGDIY KRWIILGLNK IVKMYCPVSI LDIKQGPKES FRDYVDRFYK
310 320 330 340 350 360
TLRAEQATQE VKNWMTDTLL VQNANPDCKS ILRALGPGAT LEGDEPAFQG VGGPSHKARV
370 380 390 400 410 420
LAEAMSQAQH SNDAKRQFKG PKRIVKCFNC GKEGHIARNC KAPRRKGCWK CGQEGHQMRN
430 440 450 460 470 480
CTNERQANFL GKLWPSSKGR PGNFLQKRPE PTAPPIESFG FREEEPAQKE EVKSEETENK
490
LYPQLTSLKS LFGNDPLSQ