Q197A8

PR
Gene name
IIV3-052L
Protein name
Putative DNA ligase 052L
Names
Species
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
KEGG Pathway
vg:4156302
EC number
6.5.1.2: Forming phosphoric ester bonds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

573-668 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q197A8

Entry ID Method Resolution Chain Position Source

No variants for Q197A8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q197A8

No associated diseases with Q197A8

1 regional properties for Q197A8

Type Name Position InterPro Accession
domain AAA+ ATPase domain 70 - 224 IPR003593

Functions

Description
EC Number 6.5.1.2 Forming phosphoric ester bonds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA ligase (NAD+) activity Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).

2 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYDPQFEKYN QLLKLKEKAD KAYYNGVGDP IMSDEEYDNL VDYMDELNPD GGVKTKVGAS
70 80 90 100 110 120
PSRSKSVKLP MPMNSLDKIK TQHEFDNWMK NWKPKAMLLV KEKLDGVSCL AVFTLEQNKP
130 140 150 160 170 180
PKIELFTRGD GTTGTNITRL LNHGLKVGND YCFDDMVNED KWTTDWGCYL NAEAIDHWKK
190 200 210 220 230 240
LPVKKVYIRG ELIVTRKNFQ TWYSNRFMNA RNLVSGQVNK KSPDPKILQD IDFVPYDLVI
250 260 270 280 290 300
DLKRPTMTHE VEHLLFRMIG ATPVYTRFLF LSDTISTESM ADYLERRKEK SDYEIDGLVI
310 320 330 340 350 360
QVDDDTLFAP PDNRNPKDTV AFKIMGTTAR TTVTHVEWNL SKGSKYKPTI HITPVSLSGV
370 380 390 400 410 420
TISKVTGFHG KYISENKIGK GAVVLITRSG EVIPHIVSVI SPAAKQDVLL PSNGVWKGVD
430 440 450 460 470 480
IYYDGAEEPR EITVKKMVHF FTSLGCLGLK TMTVGRLYDA GYRTVEAIVG ADTKKLVLIN
490 500 510 520 530 540
GFRMVAQKLL PSMWVNVAKA TPHELMAALN AFGEGIGLRK IQNIDCSKPE ALEVIGMTKK
550 560 570 580 590 600
TVETRIWPIW NDVLARVNAL SRMAKSQLRK QETGSCEPEE DDDYNFGSYH PCHMPCQSSN
610 620 630 640 650 660
KIWECRSRSP SAAGSASPCR PTKRRDDWFD SSESSCATET CVVESPPKKR PPMQGYVFVF
670 680 690 700 710 720
TRFRDKDLER QITALGGKVL NNVNQNVTHV ITKEKGPYKK PYTGKLKFAL DNNLFVWSLV
730 740 750
HLKSIVADEQ EKLKRQRKCR ARSPSPCGTA CSTERD