Q196Z5

PR
Gene name
IIV3-065R
Protein name
Ribonucleoside-diphosphate reductase large subunit
Names
Ribonucleotide reductase large subunit
Species
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
KEGG Pathway
vg:4156315
EC number
1.17.4.1: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q196Z5

Entry ID Method Resolution Chain Position Source

No variants for Q196Z5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q196Z5

No associated diseases with Q196Z5

3 regional properties for Q196Z5

Type Name Position InterPro Accession
domain Ribonucleotide reductase large subunit, C-terminal 82 - 442 IPR000788-1
domain Ribonucleotide reductase large subunit, C-terminal 447 - 599 IPR000788-2
domain Ribonucleotide reductase large subunit, N-terminal 11 - 78 IPR013509

Functions

Description
EC Number 1.17.4.1 With a disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.

1 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITIDESRNN LFDALGLQRL KDSYMKEDES SPQERFAFIA RQFCADDEPL AQRLYDYMSQ
70 80 90 100 110 120
HWLSPSSPQL SFGRTKQGLP IACFLPYLHD TARGLIDTWA EVSELSMIGG GIGLGVGIRQ
130 140 150 160 170 180
PDEKSVGIIP HLRTYDASCT AYKQGQTRRG SYAAYLDISH PEILSFLNTR RVGGDHNYKL
190 200 210 220 230 240
LNLHNGVNVP DSFMKKIWIL STLAPFVKMD PCPTTETLFK KAVTTLKDSR YFGADDRWLG
250 260 270 280 290 300
EVSFAALAEQ LDVVNRWDLI DPHTGKVKET IKATELWERI ILTRAETGEP YIHWIDTSNR
310 320 330 340 350 360
ALPQFQKNLG LSIRQSNLCS EVVLPTDETR TAVCCLASLN LDYFDKWCNN EQFYLDVATY
370 380 390 400 410 420
LDNVLQYFID HAPPTLKRAV HSARSERAIG IGALGFHSYL QSKMVDIESL PAYLINKKIF
430 440 450 460 470 480
KTISSHLERV NLELGELRGE APDCVGTGRR FSHMTAIAPN ATSSIIMGNT SPSCEPFRAN
490 500 510 520 530 540
IYKQDTISGS FVTYNKHLKR LLEERIPDNQ ARERVWSSIK MHDGSVQHLN QLTVQEKKVF
550 560 570 580 590 600
KTWPEINQLS LVMLAADRQK WIDQSQSTSL FFNPDERISY VHKIHLKAWL HGLKTLYYFR
610 620
SRKILTVDKV HHTTTTADPK TENDCTFCEG