Q19532

PR
Gene name
snx-17
Protein name
Sorting nexin-17 homolog
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F17H10.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q19532

Entry ID Method Resolution Chain Position Source
AF-Q19532-F1 Predicted AlphaFoldDB

No variants for Q19532

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q19532

No associated diseases with Q19532

4 regional properties for Q19532

Type Name Position InterPro Accession
domain Phox homology 67 - 176 IPR001683
domain Sorting nexin-17, FERM domain, N-terminal subdomain 182 - 293 IPR028666
domain SNX17, atypical FERM-like domain 356 - 459 IPR037836
domain Sorting nexin-17/31, FERM domain 358 - 454 IPR040842

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Early endosome
  • Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
early endosome A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol binding Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.

1 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVSSAAMARS NGDKPSTSSM EEDLEIEQSM RNASIIDHQY EKEENKNHRV LNAFDPADKT
70 80 90 100 110 120
TFSDMIHVDV PDTKTLVERS DGITKYTAYN IHINGWYHGS VRFSHLYEFA ELIKQKFSQR
130 140 150 160 170 180
YKGPEFPAKK LFKLDPKAID ERRQKITKYF QALVQHPEVA RHYLVEKKLL GFQIDSFRAT
190 200 210 220 230 240
SQYVTLDVFL GNGEKTTIKC LVSDSTLEIM KIICEKLGFK NKDQFIYHFG LFMAKGRDPT
250 260 270 280 290 300
NACYSVTTEN FNPLLTRFLR NFEAPFVSLS TANQKYNENG HYHFLCLRKL IWDSRVEEPL
310 320 330 340 350 360
LDDGNFVELL YKQAMQDYKN GHMDPVKEDL DSKLKSCMAR NDSKMFLRTC HQLSTYSYEI
370 380 390 400 410 420
MSPCSCDYPK PGTPCEIKFG RRQIIMTTRD ETGKPKPSIF RATRIRVWRI TQVMDKISFQ
430 440 450 460 470 480
FEYLMAKDTF EWITLDTDQS ILMSLLLQSI GSEILYEHNN MTIEQQVMKE KHSKGNYVEK
490 500 510 520 530
SEKLPRDPKK PIIVLKNEVE DTDPLGVMEH YHNYNRMLTT ISDGIPQRNQ AFTDITNDDL