Q18KM8
Gene name |
guaAA |
Protein name |
GMP synthase [glutamine-hydrolyzing] subunit A |
Names |
Glutamine amidotransferase |
Species |
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001) |
KEGG Pathway |
hwa:HQ_1289A |
EC number |
6.3.5.2: Carbon--nitrogen ligases with glutamine as amido-N-donor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q18KM8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q18KM8-F1 | Predicted | AlphaFoldDB |
No variants for Q18KM8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q18KM8 | |||||
No associated diseases with Q18KM8
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.5.2 | Carbon--nitrogen ligases with glutamine as amido-N-donor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| GMP synthase (glutamine-hydrolyzing) activity | Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamine metabolic process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTHIAVIDNH | GQFTHLEQRA | LRDLGVDVEL | VDNTTSPEQL | IQTADGLVLS | GGPDIDRVGN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CPEYLELDIP | ILGICLGMQL | LANELGGSVA | AGDYGGYADV | DIEILDDTDP | LIGSLAPETR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VWASHADEVK | SVPEGFERTA | RSDVCRIEAM | SNRDQERYGV | QWHPEVAHTE | RGEEVFKNFI |
| ARCQ |