Q18726

PR
Gene name
nuaf-1 (C50B8.3)
Protein name
Probable complex I intermediate-associated protein 30, mitochondrial
Names
NADH ubiquinone oxidoreductase assembly factor 1
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_C50B8.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q18726

Entry ID Method Resolution Chain Position Source
AF-Q18726-F1 Predicted AlphaFoldDB

No variants for Q18726

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q18726

No associated diseases with Q18726

1 regional properties for Q18726

Type Name Position InterPro Accession
domain NADH:ubiquinone oxidoreductase intermediate-associated protein 30 138 - 310 IPR013857

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
mitochondrial electron transport, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.
mitochondrial respiratory chain complex I assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
NADH dehydrogenase complex assembly The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9Y375 NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MITSFPVRNF LPRVTITSCA FFSKESTSAA GTVAEKKESE LQKFAGKSNL LEKKKVGIFG
70 80 90 100 110 120
TSTVPINTNF PNPKGVVDYD PDFSIKELVA ELPNTRKTQG AKLSEEIKNA FNSVSIEKTE
130 140 150 160 170 180
LLEDIGFVRH NEARVDYRFD TQEKLDLWKI GCDSDWKEGF STCSLVNSDR GTAVFSGNIS
190 200 210 220 230 240
TKVLKDGRVE RAGWASMKLE DRKAFNRKKF LSKWRNFSHL LLKVRGDGRS YKIMLHSPLS
250 260 270 280 290 300
MDFTWGDSFS HPLHTHGGPY WQYEKIPFSK FFHTVAGRIQ DRQYRVNLED TSSIGIVLMD
310 320 330
RIDGDFRLEI DYIGVYNDTT HVEDFAYETY TLPVFNTHGF