Q184M8
Gene name |
pip |
Protein name |
Proline iminopeptidase |
Names |
PIP, Prolyl aminopeptidase, PAP |
Species |
Clostridioides difficile (strain 630) (Peptoclostridium difficile) |
KEGG Pathway |
pdc:CDIF630_03325 |
EC number |
3.4.11.5: Aminopeptidases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q184M8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q184M8-F1 | Predicted | AlphaFoldDB |
No variants for Q184M8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q184M8 | |||||
No associated diseases with Q184M8
7 regional properties for Q184M8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cyclic nucleotide-binding domain | 204 - 334 | IPR000595-1 |
| domain | Cyclic nucleotide-binding domain | 336 - 452 | IPR000595-2 |
| domain | cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 5 - 43 | IPR003117 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 232 - 248 | IPR018488-1 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 280 - 297 | IPR018488-2 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 363 - 379 | IPR018488-3 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 399 - 416 | IPR018488-4 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.4.11.5 | Aminopeptidases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| aminopeptidase activity | Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKITEGYMPF | KGFKTYYRIV | GENTEGKKPL | VLLHGGPGST | HNYFEVLDKI | AESGRQVIMY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DQIGCGNSFV | EGHPELFNAD | TWIEELIELR | KHLGLDEIHL | LGQSWGGMQA | IWYAIEYKPK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GIKSYILSST | LSSAKLWEKE | QKRRISYMSE | VDQKALLDAV | NTGDYSSKEY | NDALERFMEM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YCAGEVTEDS | PECLRRPKKS | GSEAYIVGWG | QNEFSPTGTL | SGYEFTDRLH | EIKEPCLVTS |
| 250 | 260 | 270 | 280 | 290 | |
| GAIDLCSPYI | AKTMYDRIPN | SKWELFEYSR | HMPFVEENEK | YIKVLTEWLN | AND |