Q17ZX2

PR
Gene name
dapH
Protein name
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
Names
Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase
Species
Clostridioides difficile (strain 630) (Peptoclostridium difficile)
KEGG Pathway
pdc:CDIF630_03523
EC number
2.3.1.89: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

192-238 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q17ZX2

Entry ID Method Resolution Chain Position Source
AF-Q17ZX2-F1 Predicted AlphaFoldDB

No variants for Q17ZX2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q17ZX2

No associated diseases with Q17ZX2

4 regional properties for Q17ZX2

Type Name Position InterPro Accession
repeat Hexapeptide repeat 105 - 139 IPR001451-1
repeat Hexapeptide repeat 166 - 200 IPR001451-2
domain 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal 6 - 87 IPR013710
conserved_site Hexapeptide transferase, conserved site 175 - 203 IPR018357

Functions

Description
EC Number 2.3.1.89 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
tetrahydrodipicolinate N-acetyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVNLNDAYEI ARYIKEVKKK TPVKVYVNTN SLHFQSTDKF KVFGSNGSYI FVGDYEDIME
70 80 90 100 110 120
VLDKHGNDIT DTHVEYDRRN SAIPLKNTLS EHARIEPGAI IRDMVTIEKN AVVMMGAVIN
130 140 150 160 170 180
IGAVIGEGSM VDMNAVIGAR GTLGKNVHLG AGAVVAGVLE PPSATPVIVE DDVLIGANAV
190 200 210 220 230
ILEGVRIGKG AVVAAGAVVT TDVEAGAVVA GSPAKVIKMK DEKTADKTKL MEDLRNLD