Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q17TI5

Entry ID Method Resolution Chain Position Source
AF-Q17TI5-F1 Predicted AlphaFoldDB

24 variants for Q17TI5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_11447831_G_C 10 A>P No 1000Genomes
ENSVATH14034290 17 E>D No 1000Genomes
tmp_1_11447874_C_A 24 T>N No 1000Genomes
tmp_1_11448883_G_A 58 G>S No 1000Genomes
tmp_1_11448904_A_C 65 K>Q No 1000Genomes
ENSVATH01147254 70 S>P No 1000Genomes
ENSVATH12575604 73 D>N No 1000Genomes
ENSVATH14034294 75 D>E No 1000Genomes
ENSVATH01147256 103 H>N No 1000Genomes
ENSVATH04695465 124 I>V No 1000Genomes
ENSVATH04695466 125 S>F No 1000Genomes
tmp_1_11449103_T_C 131 V>A No 1000Genomes
tmp_1_11449102_G_A 131 V>I No 1000Genomes
ENSVATH01147260 137 G>E No 1000Genomes
ENSVATH12575796 141 W>* No 1000Genomes
141 W>del strain: cv. Uk-1 [UniProt] No
ENSVATH14034335 150 H>Q No 1000Genomes
ENSVATH12575797 158 T>S No 1000Genomes
ENSVATH04695470 222 M>L No 1000Genomes
ENSVATH12575800 251 S>T No 1000Genomes
tmp_1_11449756_C_A 282 S>R No 1000Genomes
tmp_1_11449817_A_G 303 I>V No 1000Genomes
ENSVATH00056929 310 T>S strain: cv. Uk-2 [UniProt] No 1000Genomes
tmp_1_11450022_A_G 335 N>S No 1000Genomes

No associated diseases with Q17TI5

1 regional properties for Q17TI5

Type Name Position InterPro Accession
domain Domain of unknown function DUF4515 84 - 265 IPR032777

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cell membrane ; Peripheral membrane protein; Cytoplasmic side
  • The translocation to the nucleus depends on the auxin concentration
  • Polar localization at the plasma membrane, rootward oriented, in developing root protophloem cells (PubMed:28652362)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.

11 GO annotations of biological process

Name Definition
auxin export across the plasma membrane The directed movement of auxins from inside of a cell, across the plasma membrane and into the extracellular region.
auxin-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
cytokinin-activated signaling pathway The series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
lateral root development The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
maintenance of root meristem identity The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
phloem development The formation of the principal food-conducting tissue of a vascular plant.
regulation of root development Any process that modulates the frequency, rate or extent of root development.
response to abscisic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
root development The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
sieve cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q84T65 BRXL4 Protein Brevis radix-like 4 Oryza sativa subsp japonica (Rice) PR
O82281 BRXL1 Protein Brevis radix-like 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYL9 BRXL2 Protein Brevis radix-like 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q5HZ09 BRXL3 Protein Brevis radix-like 3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFSCIACTKA DGGEEVEHGA RGGTTPNTKE AVKSLTIQIK DMALKFSGAY KQCKPCTGSS
70 80 90 100 110 120
SSPLKKGHRS FPDYDNASEG VPYPFMGGSA GSTPAWDFTN SSHHPAGRLE SKFTSIYGND
130 140 150 160 170 180
RESISAQSCD VVLDDDGPKE WMAQVEPGVH ITFASLPTGG NDLKRIRFSR EMFDKWQAQR
190 200 210 220 230 240
WWGENYDKIV ELYNVQRFNR QALQTPARSD DQSQRDSTYS KMDSARESKD WTPRHNFRPP
250 260 270 280 290 300
GSVPHHFYGG SSNYGPGSYH GGPPMDAART TTSSRDDPPS MSNASEMQAE WIEEDEPGVY
310 320 330 340
ITIRQLSDGT RELRRVRFSR ERFGEVHAKT WWEQNRERIQ TQYL