Q17GS9

PR
Gene name
arm
Protein name
Armadillo segment polarity protein
Names
Species
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
KEGG Pathway
aag:5576477
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

736-810 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q17GS9

Entry ID Method Resolution Chain Position Source
AF-Q17GS9-F1 Predicted AlphaFoldDB

No variants for Q17GS9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q17GS9

No associated diseases with Q17GS9

4 regional properties for Q17GS9

Type Name Position InterPro Accession
repeat Armadillo 146 - 395 IPR000225-1
repeat Armadillo 405 - 484 IPR000225-2
repeat Armadillo 482 - 592 IPR000225-3
repeat Armadillo 593 - 675 IPR000225-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cell junction, adherens junction
  • Inner surface of cell membrane and adherens junction
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cadherin binding Binding to cadherin, a type I membrane protein involved in cell adhesion.

4 GO annotations of biological process

Name Definition
canonical Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
neuroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.
segment polarity determination Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSYQMPQNRT MSHNPYNSSD MPMPSAKEQT LMWQQNSYLG DSGIHSGAVT QVPSLSGKDD
70 80 90 100 110 120
DMEDDPLMFD MDQGFSQNFT QDQVDDMNQQ LSQTRSQRVR AAMFPETLEE GIEIPSTQFD
130 140 150 160 170 180
PQQPTAVQRL SEPSQMLKHA VVNLINYQDD ADLATRAIPE LIKLLNDEDQ VVVSQAAMMV
190 200 210 220 230 240
HQLSKKEASR HAIMNSPQMV AALVRALSQS NDLETTKGAV GTLHNLSHHR QGLLAIFKSG
250 260 270 280 290 300
GIPALVKLLS SPVESVLFYA ITTLHNLLLH QDGSKMAVRL AGGLQKMVAL LQRNNVKFLA
310 320 330 340 350 360
IVTDCLQILA YGNQESKLII LASTGPSELV RIMRSYDYEK LLWTTSRVLK VLSVCSSNKP
370 380 390 400 410 420
AIVEAGGMQA LAMHLGNPSQ RLVQNCLWTL RNLSDAATKV DGLETLLSGL VTVLGSSDVN
430 440 450 460 470 480
VVTCAAGILS NLTCNNQRNK VTVCQVGGVE ALVGTIINAG DREEITEPAV CALRHLTSRH
490 500 510 520 530 540
PESESAQNIV RNGYGLPVIV KLLNPPSRWP LIKAVIGLIR NLALCPSNAA PLREHGAIHL
550 560 570 580 590 600
LVRLLFKAFQ DTQRQRSSVA TNGSQPPGAY ADGVRMEEIV EGTVGALHIL SKEELNRQLI
610 620 630 640 650 660
RQQNVISIFV QLLFYNDIEN IQRVAAGVLC ELAVDKEVAE MIEAEGATAP LTELLNSANE
670 680 690 700 710 720
GVATYAAAVL FKMSEDKSMD YKKRFSSELT TLPVFRDDTM WNNGELGIGP DLQDILSPDQ
730 740 750 760 770 780
AYEGLYGQGP PSVHSSHGGR AFQQGYDTLP IDSMQGLEIG GGGNAGPAGS NPNAGNNPGA
790 800 810 820 830
GGPPSGQPTS PYAMDMDVGE MDASELTFDH LDVMPSPPQD NNQVAAWYDT DL