Q16YB3

PR
Gene name
AAEL008605
Protein name
Inosine triphosphate pyrophosphatase
Names
ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase
Species
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
KEGG Pathway
aag:5570828
EC number
3.6.1.9: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

122-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q16YB3

Entry ID Method Resolution Chain Position Source
AF-Q16YB3-F1 Predicted AlphaFoldDB

No variants for Q16YB3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q16YB3

No associated diseases with Q16YB3

2 regional properties for Q16YB3

Type Name Position InterPro Accession
domain ABC1 atypical kinase-like domain 95 - 344 IPR004147
domain UbiB domain, bacteria 95 - 344 IPR045308

Functions

Description
EC Number 3.6.1.9 In phosphorus-containing anhydrides
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

5 GO annotations of molecular function

Name Definition
dITP diphosphatase activity Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.
ITP diphosphatase activity Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.
metal ion binding Binding to a metal ion.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
XTP diphosphatase activity Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.

2 GO annotations of biological process

Name Definition
deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRPISFVTG NAKKLEEVRA ILGPKFPREL LPVKLDLPEL QGEIDDICRK KCLEAARRVK
70 80 90 100 110 120
GPVLVEDTCL CFNALKGLPG PYIKWFLEKL EPEGLHKLLD GWEDKSAEAV CTFAYAPGED
130 140 150 160 170 180
AEVILFQGRT QGDIVYPRGC RDFGWDPIFQ PKGYDKSYAE LPKEKKNEIS HRFRALNKLR
DYFVAENQ