Q16QL3

PR
Gene name
coq2
Protein name
4-hydroxybenzoate polyprenyltransferase, mitochondrial
Names
4-HB polyprenyltransferase, Coenzyme Q biosynthesis protein 2, Para-hydroxybenzoate--polyprenyltransferase, PHB:PPT, PHB:polyprenyltransferase
Species
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
KEGG Pathway
EC number
2.5.1.39: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q16QL3

Entry ID Method Resolution Chain Position Source
AF-Q16QL3-F1 Predicted AlphaFoldDB

No variants for Q16QL3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q16QL3

No associated diseases with Q16QL3

1 regional properties for Q16QL3

Type Name Position InterPro Accession
conserved_site UbiA prenyltransferase conserved site 175 - 197 IPR030470

Functions

Description
EC Number 2.5.1.39 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.

3 GO annotations of molecular function

Name Definition
4-hydroxybenzoate decaprenyltransferase activity Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.
4-hydroxybenzoate nonaprenyltransferase activity Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.
4-hydroxybenzoate octaprenyltransferase activity Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.

4 GO annotations of biological process

Name Definition
isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
transcription by RNA polymerase I The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
transcription by RNA polymerase III The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRKLTSNSS RWTTTHLGSL WQEVGGHPIR RGLILHHHCR PLAAVSSGVI LRQKEESRWS
70 80 90 100 110 120
PNSGGKLANL RCWPEYRLHS ATKRRTLGEL VLRDYSSNNI SDKKPEPKSL LQSIVQNPYA
130 140 150 160 170 180
RLMRIDRPIG SWLLFWPCGW SIALSAPAGC WPDLWTLTLF GAGAFIMRGA GCTINDMWDR
190 200 210 220 230 240
DIDGKVARTR NRPLVAGELT SADAWFFLGA QLGVGLLILL ELNWYSIVLG ASSLGLVIIY
250 260 270 280 290 300
PLMKRITHWP QLVLGMTFNW GALLGWSATQ GSVMWSACLP LYVAGVCWTI VYDTIYAHQD
310 320 330 340 350 360
KVDDALLGIK STAIRFGDNT KLWLSGFSTA MIGGLVASGM VCEQTWPYYS AVGVISAHLA
370 380 390 400 410 420
HQIYSLNIDN PTDCATKFIS NHQVGLILFL GIVLGTLYKG YSQRAGKSST TSSSSTSSSS
430 440
SPSSGLLLAA TNHHQPARQA S