Q12VB0

PR
Gene name
ribK (Mbur_1724)
Protein name
Riboflavin kinase
Names
RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase
Species
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
KEGG Pathway
mbu:Mbur_1724
EC number
2.7.1.161: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-73 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q12VB0

Entry ID Method Resolution Chain Position Source
AF-Q12VB0-F1 Predicted AlphaFoldDB

No variants for Q12VB0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q12VB0

No associated diseases with Q12VB0

1 regional properties for Q12VB0

Type Name Position InterPro Accession
domain Riboflavin kinase domain, CTP-dependent 96 - 216 IPR023602

Functions

Description
EC Number 2.7.1.161 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
riboflavin kinase activity Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+).

3 GO annotations of biological process

Name Definition
FMN biosynthetic process The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
riboflavin biosynthetic process The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHRINALKHL ALLGALKKPV KISSSEFTRY TSTGSKTAAR ILKQLEEEGS IDRLIIPEGQ
70 80 90 100 110 120
MISITEKGHK WLESEFSDYK HIFCGDEDKV ELYGNVITGL GEGQYYIAQD GYGSQFEEKL
130 140 150 160 170 180
GFKPYPGTLN VRLTSHSADI LKRKSQKNII PISGFTDGQR TFGGCNCYFV EVEGVRGAVV
190 200 210 220
TPERSHYPHD LLEIISPVHL RKTLELNDGD EVKIMIEDRS ACE