Q12LL4

PR
Gene name
apt
Protein name
Adenine phosphoribosyltransferase
Names
APRT
Species
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
KEGG Pathway
sdn:Sden_2382
EC number
2.4.2.7: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

60-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q12LL4

Entry ID Method Resolution Chain Position Source
AF-Q12LL4-F1 Predicted AlphaFoldDB

No variants for Q12LL4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q12LL4

No associated diseases with Q12LL4

1 regional properties for Q12LL4

Type Name Position InterPro Accession
domain Phosphoribosyltransferase domain 41 - 181 IPR000836

Functions

Description
EC Number 2.4.2.7 Pentosyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
adenine phosphoribosyltransferase activity Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.

3 GO annotations of biological process

Name Definition
adenine salvage Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.
AMP salvage The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.
purine ribonucleoside salvage Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTMTMNKDSL ALIKQSIKTI ADYPKPGIMF RDVTSLLEDA SAYQATIALF VEKYQGMGFT
70 80 90 100 110 120
KVVGTEARGF LFGAPLALEL GIGFVPVRKP GKLPRKTIAQ SYELEYGMDT LEIHVDAIKP
130 140 150 160 170 180
EDKVLVVDDL LATGGTIEAT VKLIRQLGGQ VEHAAFVISL PDIGGEKRLA GLGLDVFALC
EFEGE