Q12L31
Gene name |
thiI |
Protein name |
tRNA sulfurtransferase |
Names |
Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase |
Species |
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) |
KEGG Pathway |
sdn:Sden_2566 |
EC number |
2.8.1.4: Sulfurtransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12L31
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12L31-F1 | Predicted | AlphaFoldDB |
No variants for Q12L31
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q12L31 | |||||
No associated diseases with Q12L31
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.1.4 | Sulfurtransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tRNA adenylyltransferase activity | Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1). |
| tRNA binding | Binding to a transfer RNA. |
| tRNA U4 sulfurtransferase | Catalyzes the reaction: ATP |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| thiamine biosynthetic process | +The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. |
| thiamine diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. |
| thiazole biosynthetic process | The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position. |
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFIVKLYPE | IMMKSKSVRS | RFTKMLETNI | RNVLKKVDED | AKVQRQWDRI | MVRVPADRPE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LVDAFAERLG | CIPGIAHVVQ | VNEYTFDSVD | HIYQQVLPLY | REQLAGKTFC | VRVKRTGQHD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FKSIEVERYV | GGGLNQHTDA | VGVKLKNPDL | TINLEIDHEK | LYMVVRRIEG | LGGFPMATQE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DVLSLISGGF | DSGVSSFQFI | KKGARTHYCF | FNLGGSQHEI | GVKQVAYHLW | KTYGESHKVK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FISVPFEGVV | QEILERIDNG | QMGVILKRVM | MRAATLLADK | YGIQALVTGE | SLGQVSSQTL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TNLNVIDRCT | DLLILRPLIA | MDKQDIINQS | RIIGTEDFAK | SIPEYCGVIS | QKPTVKAVLS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KIEAEELKFS | ENLIENIVAQ | AKVIDIKDIA | IEMDNQIAAA | EAETVVAVDT | QEVVIDIRAQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEEEKNPLSL | PGKTVMTIPF | FKLSTQFADL | DKSVTYLLYC | ERGVMSKLQA | LYLIEQGYTN |
| VKVYRP |