Q12FA0
Gene name |
proB |
Protein name |
Glutamate 5-kinase |
Names |
Gamma-glutamyl kinase, GK |
Species |
Polaromonas sp (strain JS666 / ATCC BAA-500) |
KEGG Pathway |
pol:Bpro_0836 |
EC number |
2.7.2.11: Phosphotransferases with a carboxy group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12FA0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12FA0-F1 | Predicted | AlphaFoldDB |
No variants for Q12FA0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q12FA0 | |||||
No associated diseases with Q12FA0
1 regional properties for Q12FA0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Acetyl-coenzyme A carboxyltransferase, C-terminal | 40 - 293 | IPR011763 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.2.11 | Phosphotransferases with a carboxy group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| glutamate 5-kinase activity | Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+). |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| L-proline biosynthetic process | The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQEKTGSPVL | RNARRIVVKV | GSSLVTNEGR | GLDADAIGLW | CEQLAALVKD | GREVIMVSSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AIAEGMKRLG | WTARPKAIHE | LQAAAAVGQM | GLAQVYESKL | RENGIGSAQV | LLTHADLADR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ERYLNARSTL | LALLQLGVVP | VINENDTVVN | DEIKFGDNDT | LGALVANLVE | ADALVILTDQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KGLYTADPRK | DPAARFVHEA | KAGDAALEAM | AGGAGSSIGK | GGMITKILAA | KRAAGSGAST |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIAWGREPQA | LIRLTQGEAI | GTLLVAQTQK | IQARKQWMAD | HLQMRGSVAV | DAGAVSKVRD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EGKSLLPIGM | TRVDGDFSRG | DVIAIRDAEG | AEIARGLANY | SSSEARLICR | KASSEFERLL |
| 370 | |||||
| GYTGEPEMVH | RTNLVLTR |