Q12340

PR
Gene name
YRM1 (YOR172W, O3620)
Protein name
Zinc finger transcription factor YRM1
Names
Reveromycin resistance modulator 1
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR172W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-223 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q12340

Entry ID Method Resolution Chain Position Source
AF-Q12340-F1 Predicted AlphaFoldDB

14 variants for Q12340

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-654584 125 G>D No SGRP
s15-654700 164 N>D No SGRP
s15-655157 316 K>I No SGRP
s15-655178 323 I>S No SGRP
s15-655411 401 D>N No SGRP
s15-655462 418 S>P No SGRP
s15-655561 451 A>T No SGRP
s15-655600 464 N>D No SGRP
s15-655602 464 N>K No SGRP
s15-655672 488 C>R No SGRP
s15-656073 621 K>N No SGRP
s15-656265 685 W>C No SGRP
s15-656342 711 L>S No SGRP
s15-656390 727 P>L No SGRP

No associated diseases with Q12340

1 regional properties for Q12340

Type Name Position InterPro Accession
domain Zn(2)Cys(6) fungal-type DNA-binding domain 25 - 70 IPR001138

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST CKTRGRSGCL
70 80 90 100 110 120
YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT EKDVALSTSP FRNPYANFYY
130 140 150 160 170 180
LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN TYNQLWSKVK IERNRWKARH KWTMKPETQL
190 200 210 220 230 240
LEGPPLEKTG SDILQQVCNV LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS
250 260 270 280 290 300
FLPSDELLPN GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS
310 320 330 340 350 360
TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL NIREIYKNQE
370 380 390 400 410 420
NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV DECENGERLP KNTNNYSSTV
430 440 450 460 470 480
FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS AFPDLAENCK KLRNFVETEF HPISYYTDSE
490 500 510 520 530 540
LISKVPLCEI KVLAQVLNLL LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC
550 560 570 580 590 600
FNLDEKHFPE FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS
610 620 630 640 650 660
NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII MARSYTFVIN
670 680 690 700 710 720
IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT DNVNTPIDPS LSDLGVTSAS
730 740 750 760 770 780
PLAGNSPGLP PEEVRNNSEN ASHNNETGPI ETELAQTISN EFWTAYNLGW EELMSQPDYK
YLFDTQ