Q12335

PR
Gene name
PST2 (YDR032C, D3422, YD9673.02C)
Protein name
Protoplast secreted protein 2
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YDR032C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q12335

Entry ID Method Resolution Chain Position Source
5MP4 X-ray 279 A A/B/C/D/E/F/G/H 1-198 PDB
AF-Q12335-F1 Predicted AlphaFoldDB

2 variants for Q12335

Variant ID(s) Position Change Description Diseaes Association Provenance
s04-504524 57 D>N No SGRP
s04-504140 185 E>Q No SGRP

No associated diseases with Q12335

2 regional properties for Q12335

Type Name Position InterPro Accession
domain NADPH-dependent FMN reductase-like 16 - 141 IPR005025
domain Flavodoxin/nitric oxide synthase 4 - 191 IPR008254

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
identical protein binding Binding to an identical protein or proteins.
NAD(P)H dehydrogenase (quinone) activity Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPRVAIIIYT LYGHVAATAE AEKKGIEAAG GSADIYQVEE TLSPEVVKAL GGAPKPDYPI
70 80 90 100 110 120
ATQDTLTEYD AFLFGIPTRF GNFPAQWKAF WDRTGGLWAK GALHGKVAGC FVSTGTGGGN
130 140 150 160 170 180
EATIMNSLST LAHHGIIFVP LGYKNVFAEL TNMDEVHGGS PWGAGTIAGS DGSRSPSALE
190
LQVHEIQGKT FYETVAKF