Q12239
Gene name |
YOL107W |
Protein name |
Transmembrane protein 115 homolog |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YOL107W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12239
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12239-F1 | Predicted | AlphaFoldDB |
5 variants for Q12239
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s15-112105 | 2 | Q>K | No | SGRP | |
| s15-112291 | 64 | T>S | No | SGRP | |
| s15-112597 | 166 | I>V | No | SGRP | |
| s15-112969 | 290 | V>I | No | SGRP | |
| s15-113059 | 320 | I>L | No | SGRP |
No associated diseases with Q12239
No regional properties for Q12239
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q12239 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQYSSRFLEL | NIPDSFLNIN | KIPDATKFIT | VTYICLTATL | FCIRRSLYNK | LVLEDPNLDY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NLITSPLLQM | VPSQIWRYPT | SLVLSNFIDT | KAWKVVVNLL | NLIIGGSFIE | RNWNSSKEMF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KFIIVLGSLT | NVLIIMLTLL | VSFFSNKVRL | DIPLDGNYTI | LIGFPIIYRQ | LLPETTIIHL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KTPQFLAKNF | RFKLLPIFVM | FTMTVTQIIW | FHHFAQLFSI | WVTFFASWSY | LRFFQKLAPL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NCPSLPTTNS | QGGQEILVGD | ASDTFQLIYF | FPDLIKPILR | PIFNFIYNVV | VVKFKVIKPF |
| 310 | 320 | 330 | 340 | ||
| HDIDIDIGNT | IAESRGAKKI | MTVEERRRQL | ALQVLEERMV | NP |