Q12232

PR
Gene name
SLP1
Protein name
Uncharacterized protein SLP1
Names
SUN-like protein 1
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR154W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

21-202 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q12232

Entry ID Method Resolution Chain Position Source
AF-Q12232-F1 Predicted AlphaFoldDB

15 variants for Q12232

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-624815 29 Q>R No SGRP
s15-624832 35 L>I No SGRP
s15-624864 45 S>R No SGRP
s15-624869 47 T>K No SGRP
s15-624931 68 R>G No SGRP
s15-624980 84 G>V No SGRP
s15-625105 126 P>A No SGRP
s15-625214 162 K>R No SGRP
s15-625379 217 S>N No SGRP
s15-625582 285 R>G No SGRP
s15-625814 362 N>S No SGRP
s15-625879 384 D>N No SGRP
s15-625975 416 Q>K No SGRP
s15-625979 417 M>K No SGRP
s15-626473 582 V>I No SGRP

No associated diseases with Q12232

1 regional properties for Q12232

Type Name Position InterPro Accession
domain SUN domain 163 - 331 IPR012919

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein folding in endoplasmic reticulum A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANRLLIYGL ILWVSIIGSF ALDRNKTAQN AKIGLHDTTV ITTGSTTNVQ KEHSSPLSTG
70 80 90 100 110 120
SLRTHDFRQA SKVDIRQADI RENGERKEQD ALTQPATPRN PGDSSNSFLS FDEWKKVKSK
130 140 150 160 170 180
EHSSGPERHL SRVREPVDPS CYKEKECIGE ELEIDLGFLT NKNEWSEREE NQKGFNEEKD
190 200 210 220 230 240
IEKVYKKKFN YASLDCAATI VKSNPEAIGA TSTLIESKDK YLLNPCSAPQ QFIVIELCED
250 260 270 280 290 300
ILVEEIEIAN YEFFSSTFKR FRVSVSDRIP MVKNEWTILG EFEARNSREL QKFQIHNPQI
310 320 330 340 350 360
WASYLKIEIL SHYEDEFYCP ISLIKVYGKS MMDEFKIDQL KAQEDKEQSI GTNNINNLNE
370 380 390 400 410 420
QNIQDRCNNI ETRLETPNTS NLSDLAGALS CTSKLIPLKF DEFFKVLNAS FCPSKQMISS
430 440 450 460 470 480
SSSSAVPVIP EESIFKNIMK RLSQLETNSS LTVSYIEEQS KLLSKSFEQL EMAHEAKFSH
490 500 510 520 530 540
LVTIFNETMM SNLDLLNNFA NQLKDQSLRI LEEQKLENDK FTNRHLLHLE RLEKEVSFQR
550 560 570 580
RIVYASFFAF VGLISYLLIT RELYFEDFEE SKNGAIEKAD IVQQAIR