Q12066
Gene name |
NUR1 (YDL089W, D2416) |
Protein name |
Nuclear rim protein 1 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YDL089W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12066
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12066-F1 | Predicted | AlphaFoldDB |
7 variants for Q12066
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s04-297184 | 122 | N>S | No | SGRP | |
| s04-297205 | 129 | Q>P | No | SGRP | |
| s04-297499 | 227 | D>V | No | SGRP | |
| s04-297889 | 357 | E>V | No | SGRP | |
| s04-297975 | 386 | H>N | No | SGRP | |
| s04-298099 | 427 | Y>F | No | SGRP | |
| s04-298213 | 465 | K>R | No | SGRP |
No associated diseases with Q12066
No regional properties for Q12066
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q12066 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nuclear membrane | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
| nuclear periphery | The portion of the nuclear lumen proximal to the inner nuclear membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maintenance of rDNA | Any process involved in sustaining the fidelity and copy number of rDNA repeats. |
| regulation of exit from mitosis | Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGSNDLINEA | YDDSEVVGEE | RESKSAWMKR | WYQLLTSPLD | LQLVINEKLE | MINWDAYAKS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LAKPLGNFLT | ILFFIIRLLQ | DNLIKPNYYK | LNVKSGAFDL | SKSNKLKEFD | YLWEISSSFQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NNNQFYAFQS | WYFVTLRFLN | NLFRFTIFIL | LSLNLYVSCK | FMFGYFKTYN | LFHLKKEFNS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PNLTKHNLKD | LSKEYYEDIY | KQSLWSMLKH | FFRGSRDDGP | HVNQNEDEIF | FQLRKWIPTN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FMINLFVSFS | PTAIVFLSFS | DVSFTSAIAI | VFHQYILDYI | ITKRFQRSVD | DDLILSSAAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QEYEDKHIMA | RINQCSNIDT | LSSAMGTRSK | TPRIFTTHSL | CGEEIREVYN | YEKREFEALP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KMTESVPGSR | ETRIKDYGGI | SQVSDHQSHP | IGFHYSPRMS | PYYRDKVLDN | NLAQSSSNEN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LEKGGAYLPN | QDQNRPSKSL | SPLRKTPLSA | RQKRFEGSEF | NVLNKNDINS | ILRSPKKKKN |
| YHKR |