Q11S94
Gene name |
bioB |
Protein name |
Biotin synthase |
Names |
|
Species |
Cytophaga hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 / NCIMB 9469 / D465) |
KEGG Pathway |
chu:CHU_2466 |
EC number |
2.8.1.6: Sulfurtransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q11S94
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q11S94-F1 | Predicted | AlphaFoldDB |
No variants for Q11S94
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q11S94 | |||||
No associated diseases with Q11S94
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.1.6 | Sulfurtransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2 iron, 2 sulfur cluster binding | Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| 4 iron, 4 sulfur cluster binding | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| biotin synthase activity | Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+). |
| iron ion binding | Binding to an iron (Fe) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| biotin biosynthetic process | The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEIRNNWTK | EEISAIYNSP | ILDLMYRGAT | VHREFHDPQE | VQVCTLLSIK | TGGCPEDCSY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CPQAARYHTD | VKVEKLMDVK | DVLNSALEAK | ESGSTRFCMG | AAWREVRDNK | DFDKVIDMVK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GVSTMGMEVC | CTLGMLTPEQ | ADKLKDAGLY | AYNHNLDTSA | EHYDKVITTR | TYDDRLETLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NVRNAKISVC | SGGIIGMGES | HGDRVGMLHT | LANMVEHPES | VPVNALVPVE | GTPLEDQPRV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SVWEMVRMIA | TARIIMPKAM | VRLSAGRVRM | NTEEQALCFL | AGANSIFAGD | KLLTTPNPEV |
| 310 | 320 | 330 | |||
| NADKEMFQVL | NLKPRQSFKN | GDAPKIKFEQ | IPSALVK |