Q10138

PR
Gene name
SPAC3H8.02
Protein name
CRAL-TRIO domain-containing protein C3H8.02
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC3H8.02
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-110 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q10138

Entry ID Method Resolution Chain Position Source
AF-Q10138-F1 Predicted AlphaFoldDB

4 variants for Q10138

Variant ID(s) Position Change Description Diseaes Association Provenance
I_589100_G_A 59 R>H No Jeffares_SNPs
I_589145_T_C 74 L>P No Jeffares_SNPs
I_589276_G_A 118 V>I No Jeffares_SNPs
I_589408_G_A 162 V>I No Jeffares_SNPs

No associated diseases with Q10138

2 regional properties for Q10138

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 171 - 330 IPR001251
domain CRAL/TRIO, N-terminal domain 104 - 148 IPR011074

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
phospholipid transfer activity Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

1 GO annotations of biological process

Name Definition
intermembrane phospholipid transfer The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPEGAGRPWN LTELEEEKLK TMWSYLFKLF GITLLERTES WYTVKTHLSD DSSSSSSHRL
70 80 90 100 110 120
SSVSYAKSRT RLELTSSSHG SDTRSFNDKT KNVHLERVEK IASEWDPEGL RVCFWDAVNC
130 140 150 160 170 180
DDPDGLLLRF LRARKWNVEA ALEMFMKTVH WRSREMNVGE IVCNADHLDK DDDFVRQLRI
190 200 210 220 230 240
GKCFIFGEDK HNRPVCYIRA RLHKVGDVSP ESVERLTVWV METARLILKP PIETATVVFD
250 260 270 280 290 300
MTDFSMSNMD YGPLKFMIKC FEAHYPECLG ECIVHKAPWL FQGVWSIIKS WLDPVVVSKV
310 320 330 340 350 360
KFTRNYRDLQ QYINPDNILK EFGGPNPWRY TYPEPCQNEA EALKNVEARK SLRAKKDAIA
370 380 390 400 410 420
KQYEEVTMDW ILNNGDMAEV KQKRRKLASQ LIDAYWNLDK YIRARSVYDR MGLIAPQTSH
430 440
TLLLSQPTNG DVKESMVEVT SSAT