Q0ZME3

PR
Gene name
N
Protein name
Nucleoprotein
Names
Nucleocapsid protein, NC, Protein N
Species
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

171-241 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q0ZME3

Entry ID Method Resolution Chain Position Source

No variants for Q0ZME3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0ZME3

No associated diseases with Q0ZME3

2 regional properties for Q0ZME3

Type Name Position InterPro Accession
domain Nucleocapsid (N) protein, C-terminal domain, coronavirus 257 - 379 IPR044344
domain Nucleocapsid (N) protein, N-terminal domain, coronavirus 60 - 189 IPR044345

Functions

Description
EC Number
Subcellular Localization
  • Virion
  • Host endoplasmic reticulum-Golgi intermediate compartment
  • Host Golgi apparatus
  • Located inside the virion, complexed with the viral RNA
  • Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
host cell endoplasmic reticulum-Golgi intermediate compartment A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.
host cell Golgi apparatus A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSYTPGHHAG SRSSSGNRSG ILKKTSWVDQ SERSHQTYNR GRKPQPKFTV STQPQGNPIP
70 80 90 100 110 120
HYSWFSGITQ FQKGRDFKFP DGQGVPIAYG IPPSEAKGYW YKHNRRSFKT ADGQQKQLLP
130 140 150 160 170 180
RWYFYYLGTG PYASSSYGDA HEGIFWVASH QADTSIPSDV SARDPTIQEA IPTRFSPGTI
190 200 210 220 230 240
LPQGYYVEGS GRSASNSRPG SRSQSRGPNN RSLSRSNSNF RHSDSIVKPD MADEIASLVL
250 260 270 280 290 300
AKLGKDSKPQ QVTKQNAKEI RHKILMKPRQ KRTPNKFCNV QQCFGKRGPL QNFGNSEMLK
310 320 330 340 350 360
LGTNDPQFPI LAELAPTPGA FFFGSKLELF KRDSDADSPS KDTFELRYSG SIRFDSTLPG
370 380 390 400 410 420
FETIMKVLKE NLDAYVNSNQ NTVSGSLSPK PQRKRGVKQS PESFDSLNLS ADTQHISNDF
430 440
TPEDHSLLAT LDDPYVEDSV A