Q0WPZ7
PR
Gene name |
GLE1 |
Protein name |
mRNA export factor GLE1 |
Names |
GLE1-like protein, Nucleoporin GLE1, Protein EMBRYO DEFECTIVE 1745, Protein GLE1, AtGLE1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G13120 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0WPZ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0WPZ7-F1 | Predicted | AlphaFoldDB |
61 variants for Q0WPZ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01045080 | 2 | G>R | No | 1000Genomes | |
| ENSVATH11118532 | 9 | C>F | No | 1000Genomes | |
| ENSVATH01045079 | 13 | V>I | No | 1000Genomes | |
| ENSVATH11118531 | 16 | I>V | No | 1000Genomes | |
| tmp_1_4472586_T_G | 25 | N>H | No | 1000Genomes | |
| ENSVATH00021149 | 27 | E>D | No | 1000Genomes | |
| ENSVATH13889064 | 41 | N>K | No | 1000Genomes | |
| tmp_1_4472505_T_C | 52 | N>D | No | 1000Genomes | |
| ENSVATH01045073 | 60 | R>S | No | 1000Genomes | |
| tmp_1_4472284_C_T | 85 | E>K | No | 1000Genomes | |
| ENSVATH00021142 | 113 | E>D | No | 1000Genomes | |
| tmp_1_4472088_G_A | 117 | H>Y | No | 1000Genomes | |
| tmp_1_4472034_C_T | 135 | E>K | No | 1000Genomes | |
| tmp_1_4472018_T_A | 140 | H>L | No | 1000Genomes | |
| ENSVATH04568552 | 141 | Q>R | No | 1000Genomes | |
| tmp_1_4472010_C_T | 143 | E>K | No | 1000Genomes | |
| ENSVATH01045061 | 212 | I>M | No | 1000Genomes | |
| ENSVATH01045060 | 227 | Q>* | No | 1000Genomes | |
| ENSVATH01045059 | 227 | Q>L | No | 1000Genomes | |
| tmp_1_4471512_C_T | 231 | R>K | No | 1000Genomes | |
| tmp_1_4471462_G_A,T | 248 | R>C | No | 1000Genomes | |
| tmp_1_4471462_G_A,T | 248 | R>S | No | 1000Genomes | |
| tmp_1_4471420_C_T | 262 | E>K | No | 1000Genomes | |
| tmp_1_4471399_T_A | 269 | K>* | No | 1000Genomes | |
| tmp_1_4471398_T_A | 269 | K>M | No | 1000Genomes | |
| ENSVATH04568547 | 282 | R>C | No | 1000Genomes | |
| ENSVATH04568546 | 286 | E>K | No | 1000Genomes | |
| ENSVATH01045057 | 287 | Q>H | No | 1000Genomes | |
| ENSVATH11118529 | 287 | Q>L | No | 1000Genomes | |
| ENSVATH11118528 | 289 | L>R | No | 1000Genomes | |
| ENSVATH01045056 | 298 | S>N | No | 1000Genomes | |
| tmp_1_4471270_C_A | 312 | G>C | No | 1000Genomes | |
| ENSVATH04568543 | 314 | S>L | No | 1000Genomes | |
| tmp_1_4471130_G_A | 318 | A>V | No | 1000Genomes | |
| ENSVATH01045051 | 337 | T>S | No | 1000Genomes | |
| ENSVATH11118174 | 390 | S>A | No | 1000Genomes | |
| ENSVATH00021133 | 392 | S>N | No | 1000Genomes | |
| ENSVATH01045037 | 425 | Q>L | No | 1000Genomes | |
| tmp_1_4470118_G_C | 435 | H>D | No | 1000Genomes | |
| ENSVATH01045036 | 437 | A>G | No | 1000Genomes | |
| tmp_1_4470078_T_A | 448 | N>I | No | 1000Genomes | |
| tmp_1_4470072_T_G | 450 | Q>P | No | 1000Genomes | |
| ENSVATH11118173 | 453 | W>L | No | 1000Genomes | |
| tmp_1_4469943_T_C | 465 | M>V | No | 1000Genomes | |
| ENSVATH11118171 | 471 | L>F | No | 1000Genomes | |
| ENSVATH00021127 | 475 | D>N | No | 1000Genomes | |
| ENSVATH00021126 | 477 | R>C | No | 1000Genomes | |
| tmp_1_4469819_C_T,A | 477 | R>H | No | 1000Genomes | |
| tmp_1_4469819_C_T,A | 477 | R>L | No | 1000Genomes | |
| ENSVATH04568529 | 478 | V>I | No | 1000Genomes | |
| ENSVATH04568529 | 478 | V>L | No | 1000Genomes | |
| tmp_1_4469766_C_A | 495 | A>S | No | 1000Genomes | |
| ENSVATH13889062 | 503 | A>V | No | 1000Genomes | |
| tmp_1_4469569_A_C | 534 | V>G | No | 1000Genomes | |
| tmp_1_4469534_G_A | 546 | R>W | No | 1000Genomes | |
| ENSVATH01045033 | 549 | K>R | No | 1000Genomes | |
| tmp_1_4469500_A_G | 557 | I>T | No | 1000Genomes | |
| ENSVATH11118166 | 568 | R>W | No | 1000Genomes | |
| tmp_1_4469383_G_A | 596 | P>L | No | 1000Genomes | |
| tmp_1_4469381_T_C | 597 | N>D | No | 1000Genomes | |
| tmp_1_4469356_T_C | 605 | N>S | No | 1000Genomes |
No associated diseases with Q0WPZ7
No regional properties for Q0WPZ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q0WPZ7 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nuclear envelope | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). |
| nuclear pore cytoplasmic filaments | Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| inositol hexakisphosphate binding | Binding to inositol hexakisphosphate. |
| phospholipid binding | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. |
| translation initiation factor binding | Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA export from nucleus | The directed movement of mRNA from the nucleus to the cytoplasm. |
| poly(A)+ mRNA export from nucleus | The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of translational initiation | Any process that modulates the frequency, rate or extent of translational initiation. |
| regulation of translational termination | Any process that modulates the frequency, rate or extent of translational termination. |
| seed development | The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGIVLEPPCP | KSVDGISIDP | EPNWNFESLV | AEIASVEKKL | NGFSMYPQPI | TNTTLRMGRR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GGGFVMHVSE | DEMESDEGEE | SDDEEEEEDH | SQICTAGKRF | ACDELYLSDE | SDEEFDHEPE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YMMNKLGLAE | SALYEVINDH | QTEIKDDIRN | QVSVVETEIM | NEIETSLSAI | ARVEKYSETR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEVERKLDLQ | YQRKVAEALD | THLTAVQREH | KIKSQIEERK | IRSEEAQEEA | RRKERAHQEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KIRQEKARAE | AQMLAKIRAE | EEKKEVERKA | AREVAEKEVA | DRKAAEQKLA | EQKAVIESVT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GSSATSNAQA | GGNSIRAAES | ALILENHRLK | KLEELETTNQ | SLKSRSNENF | SSFEKHIGRV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IRQISGTKDS | VSGKINDIVK | IFKDPRCPVS | ISIAAFAKKM | VTTKEKPNPF | ACSYVIVYIN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SQFPQVMDIL | LAEFHKACIY | TVPKHIVNSQ | SAWDSDAYER | LDSIMRLYGA | LVQTDIRVGN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ATNVHGIEHG | WAWLARFLNK | IPANRATATA | LNSFLQTAGF | GLHQRYKSQF | LKVVNVVREH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FLQKLRAKKD | TSDLLVIIAE | ITAYLDDRMY | LKEPEGRAMK | TTSTLSSELT | AELNQPNYNQ |
| 610 | |||||
| NYQRNDYRNY | Y |