Q0W6S4
Gene name |
purO |
Protein name |
IMP cyclohydrolase |
Names |
IMP synthase, Inosinicase |
Species |
Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) |
KEGG Pathway |
rci:RCIX491 |
EC number |
3.5.4.10: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0W6S4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0W6S4-F1 | Predicted | AlphaFoldDB |
No variants for Q0W6S4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0W6S4 | |||||
No associated diseases with Q0W6S4
1 regional properties for Q0W6S4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Inosine monophosphate cyclohydrolase-like | 2 - 189 | IPR020600 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.10 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| IMP cyclohydrolase activity | Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' IMP biosynthetic process | The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYVGRFVTIG | KTNGRLWAGY | RVSSRSFPNR | YAVKLGDDKV | AIMPKDVKDL | EKSPYISYNC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IRVLPSVAVV | TNGSHTDAIV | EKIEMGYPIR | DALALSLLAM | DYEKDSLDTP | RIAAVVSRHV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AYLGIVTKDG | LNVSTFPMGD | NECLMVATYE | KTMFSRLTVD | ASSAEEVARK | MYDLTFEKPV |
| 190 | 200 | ||||
| CAAGAYQVDD | HFELGVYNGP | Q |